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Full-Text Articles in Pharmacology, Toxicology and Environmental Health
Co-Crystallization Of Urea Granules For Slower Dissolution, Vidya Nagaraju, Carl Wassgren, Kingsly Ambrose
Co-Crystallization Of Urea Granules For Slower Dissolution, Vidya Nagaraju, Carl Wassgren, Kingsly Ambrose
Graduate Industrial Research Symposium
Co-crystals are multicomponent crystals formed through hydrogen bond interactions. Co-crystallization, the process of developing cocrystals, serves as a versatile approach for discovering new solid forms of active ingredients (AIs) that can alter physical properties such as solubility, dissolution rates, and stability. These co-crystals can be produced through three main methods: solid-state methods, solution-based methods, and supercritical fluid methods. Recently, the solid-state (mechanochemical) method of developing cocrystals has gained more attention from researchers in the development of slow-release urea fertilizers. This technique can also be applied to the development of urease inhibitors. These multicomponent crystals present a potential solution to the …
Nucleic Acid Detection Of Live Pathogens On Contaminated Foods, Simerdeep Kaur, Mohit Verma
Nucleic Acid Detection Of Live Pathogens On Contaminated Foods, Simerdeep Kaur, Mohit Verma
Graduate Industrial Research Symposium
The goal is to develop a point-of-care biosensor for the detection of live pathogens contaminating beef products. Biosensing of live pathogens is based on isothermal amplification of nucleic acid on a paper-based device. A colorimetric dye is employed as an indicator of the amplification product for visual result. The assay incorporates a compound Propidium monoazide (PMA) that makes the DNA from dead cells inaccessible for amplification. This approach is especially applicable for pathogens that can enter a viable but non-culturable state (VBNC).
Full-Water Column Turbulence Parameterization Of Stratified Waters In Southern Lake Michigan, Kyla A. Prendergast, Cary D. Troy, David Cannon
Full-Water Column Turbulence Parameterization Of Stratified Waters In Southern Lake Michigan, Kyla A. Prendergast, Cary D. Troy, David Cannon
The Summer Undergraduate Research Fellowship (SURF) Symposium
Full water column mean flow and turbulence structure was characterized at two stratified locations in Lake Michigan (a. Muskegon, MI; b. Michigan City, IN) in order to better understand the filtration potential of invasive quagga mussels. Invasive quagga mussels in Lake Michigan are filter feeders and can dramatically alter clarity as well as the biological/chemical characteristics of the water column. This filtering capacity is highly contingent on turbulence characteristics throughout the water column, which is poorly understood in the Great Lakes. Using velocity, temperature, and turbulence data collected from these locations, the structure of the water column turbulence was modeled …