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Full-Text Articles in Pharmacology, Toxicology and Environmental Health
Interactions Between Soft Nanoparticles And Mammalian Cells, Mitchell Raith
Interactions Between Soft Nanoparticles And Mammalian Cells, Mitchell Raith
Doctoral Dissertations
Nanoparticles have been of interest to the pharmaceutical industry since the 1980s. The first FDA approved nanoparticle-based therapies included liposomal anesthesia agents. Since then, the amount of FDA-approved nanoparticle therapies remains low. This is because nanoparticle-patient interactions can be very complex and are not well understood. Complicating factors also include increasing obesity rates among the patient population and many small animal pre-clinical trials are completed with healthy, lean animals. The biochemical differences between lean and obese patients prevents early studies from accurately predicting nanoparticle clinical behaviors. Many nanoparticles fail in trails. In this thesis, I aimed to uncover how nanoparticles …
Removal Of Trace Organic Compounds In Domestic Wastewater Using Recirculating Packed-Bed Media Filters, Brittani Nikole Perez
Removal Of Trace Organic Compounds In Domestic Wastewater Using Recirculating Packed-Bed Media Filters, Brittani Nikole Perez
Masters Theses
Pharmaceuticals and personal care products (PPCPs) are commonly detected in the environment resulting from their survival from conventional wastewater treatment systems. More information is needed about the fate and transfer of these trace organic compounds in domestic wastewater and their associated risks so that efficient strategies for their removal can be developed for both large/small scale treatment systems. This study aimed to determine whether onsite wastewater treatment systems were capable of providing PPCP removal, in addition to quantifying different forms of removal (biodegradation/sorption). A column study was constructed to determine the removal efficiencies of 3 target PPCPs, endocrine disrupting compound …