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Full-Text Articles in Pharmacology, Toxicology and Environmental Health
The Effects Of Water And Habitat Quality On Amphibian Assemblages In Two Midwest Watersheds, Abel Castaneda, Mark Jordan
The Effects Of Water And Habitat Quality On Amphibian Assemblages In Two Midwest Watersheds, Abel Castaneda, Mark Jordan
Mark A. Jordan
No abstract provided.
Interaction Of Fish Aryl Hydrocarbon Receptor Paralogs (Ahr1 And Ahr2) With The Retinoblastoma Protein, Rebeka Merson, Sibel Karchner, Mark Hahn
Interaction Of Fish Aryl Hydrocarbon Receptor Paralogs (Ahr1 And Ahr2) With The Retinoblastoma Protein, Rebeka Merson, Sibel Karchner, Mark Hahn
Rebeka Rand Merson
The aryl hydrocarbon receptor (AHR) mediates the toxic effects of 2,3,7,8-tetrachlorodibenzo-pdioxin (TCDD) and related compounds. In some mammalian cell lines, TCDD induces G1 cell cycle arrest, which depends on an interaction between the AHR and the retinoblastoma tumor suppressor (RB). Mammals possess one AHR, whereas fishes possess two or more AHR paralogs that differ in the domains important for AHR-RB interactions in mammals. To test the hypothesis that fish AHR paralogs differ in their ability to interact with RB, we cloned RB cDNA from Atlantic killifish, Fundulus heteroclitus, and studied the interactions of killifish RB protein with killifish AHR1 and …
Occurrence And Biological Effect Of Exogenous Steroids In The Elkhorn River, Nebraska, Usa, Alan Kolok, Daniel Snow, Satomi Kohno, Marlo Sellin, Louis Guillette
Occurrence And Biological Effect Of Exogenous Steroids In The Elkhorn River, Nebraska, Usa, Alan Kolok, Daniel Snow, Satomi Kohno, Marlo Sellin, Louis Guillette
Daniel D Snow
Recent studies of surface waters in North America, Japan, and Europe have reported the presence of steroidogenic agents as contaminants. The current study has three objectives: 1) to determine if steroidogenic compounds are present in the Elkhorn River, 2) to determine if sediments collected from the Elkhorn River can act as a source of steroidogenic compounds to aquatic organisms, and 3) to determine if site-specific biological effects are apparent in the hepatic gene expression of fathead minnows. Evidence was obtained using three approaches: 1) deployment of polar organic chemical integrative samplers (POCIS), 2) deployment of caged fathead minnows, and 3) …
Environmental Issues For The 21st Century And Their Impact On Human Health, Richard B. Philp
Environmental Issues For The 21st Century And Their Impact On Human Health, Richard B. Philp
Richard B. Philp
This book (see contents attached) is now available from the author on CD