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Articles 1 - 4 of 4
Full-Text Articles in Nutrition
Rac1 And Ire1 Are Required To Prevent Early Loss Of Intestinal Homeostasis In Drosophila Melanogaster, Mauricio M. Ortega
Rac1 And Ire1 Are Required To Prevent Early Loss Of Intestinal Homeostasis In Drosophila Melanogaster, Mauricio M. Ortega
Dissertations, Masters Theses, Capstones, and Culminating Projects
No abstract available
The Role Of Cdk5r1 In Β-¬Cell Survival From Apoptosis, Amanda Hobson, Jeffrey Tessem
The Role Of Cdk5r1 In Β-¬Cell Survival From Apoptosis, Amanda Hobson, Jeffrey Tessem
Journal of Undergraduate Research
Type 1 and Type 2 diabetes are classified as a decrease in functional ß-cell mass, which results in impaired blood glucose regulation. Functional ß-cell mass is defined as the glucose stimulated insulin secretion rate multiplied by the total cellular mass which is determined by the proliferation and cell death rates. Though ß-cell mass proliferation rates generally decrease by adolescence, obesity and pregnancy have been shown to be times of significant ß-cell proliferation (1). This implies that the inherent molecular pathways necessary for ß-cell proliferation are present, but highly regulated. Discovering the molecular pathway of ß-cell proliferation could lead to diabetes …
Determining If C-Fos Protects Β-Cells From Apoptosis, Kyle Kener, Jeffery Tessem
Determining If C-Fos Protects Β-Cells From Apoptosis, Kyle Kener, Jeffery Tessem
Journal of Undergraduate Research
Diabetes, a disease characterized by the inability of the body to maintain a normal blood glucose level, continues to affect the lives of many. In both Type I and Type II diabetes, eventual β-cell destruction results in decreased β-cell mass. Regeneration of functional β-cells and protection of such, could help reverse the effects of this disease and could possibly lead to a cure. Many studies have been done to increase functioning β-cell mass, but protecting regenerated β-cells from further apoptotic insults could greatly increase the effectiveness of β-cell transplants and other future treatments of the disease.
Regulation Of Obesity And Metabolic Complications By Gamma And Delta Tocotrienols, Lu Zhao, Xiefan Fang, Maurice R. Marshall, Soonkyu Chung
Regulation Of Obesity And Metabolic Complications By Gamma And Delta Tocotrienols, Lu Zhao, Xiefan Fang, Maurice R. Marshall, Soonkyu Chung
Department of Nutrition and Health Sciences: Faculty Publications
Tocotrienols (T3s) are a subclass of unsaturated vitamin E that have been extensively studied for their anti-proliferative, anti-oxidative and anti-inflammatory properties in numerous cancer studies. Recently, T3s have received increasing attention due to their previously unrecognized property to attenuate obesity and its associated metabolic complications. In this review, we comprehensively evaluated the recent published scientific literature about the influence of T3s on obesity, with a particular emphasis on the signaling pathways involved. T3s have been demonstrated in animal models or human subjects to reduce fat mass, body weight, plasma concentrations of free fatty acid, triglycerides and cholesterol, as well as …