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Can Cranberry Supplementation Reduce Risks For Diabetes?, Belinda K. Chambers

Electronic Theses and Dissertations

Diabetes affects approximately 250 million people worldwide and health care costs related to diabetes equal approximately $98 billion each year. Aldose reductase has been shown to contribute to the side effects of diabetes including kidney disease, nerve disease, and retinopathy. Cranberries contain anthocyanins and other flavonoids that have been shown in vitro to inhibit the enzyme aldose reductase and to inhibit protein glycosylation. It is believed that daily cranberry supplementation could reduce side effects of diabetes. Twenty-seven adults with type 2 diabetes were recruited for this 12 week double-blind, placebo-controlled study. Fasting blood analysis was done at weeks 0, 6, …