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Nkx6.1 And Stx1a As Binding Partners In Pancreatic Beta Cells, Jakob T. Lenker, Jeff S. Tessem, Connor C. Littlefield
Nkx6.1 And Stx1a As Binding Partners In Pancreatic Beta Cells, Jakob T. Lenker, Jeff S. Tessem, Connor C. Littlefield
Library/Life Sciences Undergraduate Poster Competition 2024
Diabetes is characterized by a loss in beta cell function within the pancreas and the subsequent inability to produce sufficient insulin to regulate blood glucose. While current diabetes treatments focus on delivering pharmaceutical insulin to diabetic individuals, such treatments are temporary solutions and do not address the root of the issue. Instead, our research focuses on potential mechanisms for inducing greater insulin secretion within the pancreas of the individual. NK6 Homeobox 1 (Nkx6.1) is a major transcription factor in beta cells and its overexpression in beta cells is associated with higher insulin secretion. Previous research indicates that Syntaxin 1A (Stx1A) …