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Full-Text Articles in Neuroscience and Neurobiology
What Makes An Image Memorable? Effects Of Encoding On The Mechanism Of Recognition, Asiya Gul
What Makes An Image Memorable? Effects Of Encoding On The Mechanism Of Recognition, Asiya Gul
Theses and Dissertations (Comprehensive)
Memory is undoubtedly one of the most important processes of human cognition. A long line of research suggests that recognition relies on the assessment of two explicit memory phenomena: familiarity and recollection. Researchers who support the Dual Process Signal Detection (DPSD) model of recognition memory link the FN400 component (a negative ERP deflection peaking around 400 ms at frontal electrodes) with familiarity; however, it is currently unclear whether the FN400 reflects familiarity or implicit memory. Three event-related potentials (ERP) studies were conducted to determine whether implicit memory plays a role in setting up encoding strategies, and how these encoding strategies …
Testing The Network Reset Hypothesis: Noradrenergic Modulation Of Hippocampal Representations, Stephanie L. Grella
Testing The Network Reset Hypothesis: Noradrenergic Modulation Of Hippocampal Representations, Stephanie L. Grella
Theses and Dissertations (Comprehensive)
The locus coeruleus (LC) responds to salience cues, including novelty, and sends a major noradrenergic projection to the hippocampal formation (HF). Novelty-associated LC activation may help to sculpt contextual representations in the HF, but modulatory influence of norepinephrine (NE) over HF representations remains poorly understood. One possible mechanism is that NE provides a “reset” signal causing the HF to recruit distinct neural populations, thereby providing a molecular switch to dictate if hippocampal circuits should generate new representations or update existing ones to incorporate novel information. This hypothesis suggests that NE release should cause the HF to recruit a unique population …