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Full-Text Articles in Neuroscience and Neurobiology
Immunolesions Using Site Specific Injections Of 192-Lgg Saporin Into The Basal Forebrain Fail To Affect Radial Arm Maze Performance In The Male Rat, Lesley J. Hickman '96
Immunolesions Using Site Specific Injections Of 192-Lgg Saporin Into The Basal Forebrain Fail To Affect Radial Arm Maze Performance In The Male Rat, Lesley J. Hickman '96
Honors Projects
In this study I investigated the effects of 192-lgG saporin injections into the medial septal area.(MSA) and nucleus basalis magnocel/ularis (NBM) on radial arm maze performance in the male rat. The results of the present study reveal that combined injections of 192-lgG saporin into the basal forebrain failed to disrupt RAM performance when compared to vehicle-injected controls. In addition, intraperitoneal injections using a muscarinic receptor blocker, scopolamine, failed to reveal a compensatory response of the cholinergic basal forebrain that may have explained the lack of behavioral effects of 192IgG saporin. Consequently, the results of this study suggest that a selective …
Topographically Specific Effects Of Elf-1 On Retinal Axon Guidance In Vitro And Retinal Axon Mapping In Vivo, Masaru Nakamoto
Topographically Specific Effects Of Elf-1 On Retinal Axon Guidance In Vitro And Retinal Axon Mapping In Vivo, Masaru Nakamoto
Biology Faculty Publications
Topographic maps, which maintain the spatial order of neurons in the order of their axonal connections, are found throughout the nervous system. In the visual retinotectal projection, ELF-1, a ligand in the tectum, and its receptors in the retina show complementary gradients in expression and binding, indicating they may be positional labels for map development. Here we show that ELF-1 acts as a repellent axon guidance factor in vitro. In vivo, when the tectal ELF-1 pattern is modified by retroviral overexpression, retinal axons avoid ectopic ELF-1 patches and map to abnormally anterior positions. All these effects were seen on axons …
The Effects Of Aging And Musical Experience On The Representation Of Tonal Hierarchies, Andrea Halpern, S.Y. Kwak, J.C. Bartlett, W.J. Dowling
The Effects Of Aging And Musical Experience On The Representation Of Tonal Hierarchies, Andrea Halpern, S.Y. Kwak, J.C. Bartlett, W.J. Dowling
Faculty Journal Articles
Two experiments explored the representation of the tonal hierarchy in Western music among older (aged 60 to 80) and younger (aged 15 to 22) musicians and nonmusicians. A probe tone technique was used: 4 notes from the major triad were presented, followed by 1 note chosen from the 12 notes of the chromatic scale. Whereas musicians had a better sense of the tonal hierarchy than nonmusicians, older adults were no worse than younger adults in differentiating the notes according to musical principles. However, older adults were more prone than younger adults to classify the notes by frequency proximity (pitch height) …
Hearing In The Mind's Ear: A Pet Investigation Of Musical Imagery And Perception, Robert J. Zatorre, Andrea R. Halpern, David W. Perry, Ernst Meyer, Alan C. Evans
Hearing In The Mind's Ear: A Pet Investigation Of Musical Imagery And Perception, Robert J. Zatorre, Andrea R. Halpern, David W. Perry, Ernst Meyer, Alan C. Evans
Faculty Journal Articles
Neuropsychological studies have suggested that imagery processes may be mediated by neuronal mechanisms similar to those used in perception. To test this hypothesis, and to explore the neural basis for song imagery, 12 normal subjects were scanned using the water bolus method to measure cerebral blood flow (CBF) during the performance of three tasks. In the control condition subjects saw pairs of words on each trial and judged which word was longer. In the perceptual condition subjects also viewed pairs of words, this time drawn from a familiar song; simultaneously they heard the corresponding song, and their task was to …