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Full-Text Articles in Neuroscience and Neurobiology
Ab42 Alters Glutamatergic Transmission In The Ca1 Region Of The Mouse Hippocampus, Patrick Harry Wehrle
Ab42 Alters Glutamatergic Transmission In The Ca1 Region Of The Mouse Hippocampus, Patrick Harry Wehrle
Legacy Theses & Dissertations (2009 - 2024)
Alzheimer’s disease (AD) is a neurodegenerative disease affecting 4.5 million people in the US, a number expected to increase 3-fold over the next 30 years. One of the hallmarks of AD is the extracellular accumulation of the protein Aß₄₂ throughout in the brain, particularly in limbic structures like the temporal cortex and hippocampus, key regions for learning and memory. Currently available animal models for AD aim to reproduce key genetic traits of the familial variant of the disease, but >90% of AD patients are affected by idiopathic AD. To overcome this potential limitation, we use a different approach to study …
Disease In A Dish : Modeling Tau Pathology For Future Antibody Testing, Leneea Toyisha Warner
Disease In A Dish : Modeling Tau Pathology For Future Antibody Testing, Leneea Toyisha Warner
Legacy Theses & Dissertations (2009 - 2024)
ABSTRACT