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Full-Text Articles in Neuroscience and Neurobiology
Risk Profiles For Adolescent Internalizing Problems, Kelsey Elizabeth Hudson
Risk Profiles For Adolescent Internalizing Problems, Kelsey Elizabeth Hudson
Graduate College Dissertations and Theses
Objective: Internalizing problems are commonly diagnosed during adolescence, and are associated with distress, impairment, and negative mental health outcomes in adulthood. Thus, there is a critical need to characterize adolescents who are at the highest risk for escalating to clinical levels of internalizing problems while extending current literature and incorporating both biological and environmental predictors. This study aimed to characterized risk profiles for fourteen-year-old adolescents who developed clinical levels of internalizing (High Internalizing [HI]) problems by age nineteen, using brain, genetic, personality, cognitive, life history, psychopathology, and demographic measures. The study also examined whether there were functional and structural brain …
The Role Of Estrogen In Emotional And Cognitive Processes Integral To Major Depressive Disorder, Kimberly Albert
The Role Of Estrogen In Emotional And Cognitive Processes Integral To Major Depressive Disorder, Kimberly Albert
Graduate College Dissertations and Theses
Women have greater incidence and prevalence of Major Depressive Disorder (MDD) than men during the reproductive life phase when ovarian hormones fluctuate, suggesting that ovarian hormones have a significant role in MDD etiology in women. As the core symptoms of MDD are indicative of alterations in stress responding, emotional processing, and mood regulation, examining the effects of the estrogen on these processes in women may provide a better understanding of the role of estrogen in the sex difference in MDD rates. The general aim of this dissertation was to examine neural, emotional, and attentional processes related to stress response alterations …