Open Access. Powered by Scholars. Published by Universities.®
Neuroscience and Neurobiology Commons™
Open Access. Powered by Scholars. Published by Universities.®
- Discipline
-
- Behavior and Behavior Mechanisms (1)
- Behavioral Neurobiology (1)
- Biology (1)
- Cognitive Behavioral Therapy (1)
- Cognitive Neuroscience (1)
-
- Congenital, Hereditary, and Neonatal Diseases and Abnormalities (1)
- Diseases (1)
- Genetics (1)
- Genetics and Genomics (1)
- Geriatric Nursing (1)
- Geriatrics (1)
- Health Services Research (1)
- Health and Medical Administration (1)
- Medical Education (1)
- Medical Specialties (1)
- Medicine and Health Sciences (1)
- Mental Disorders (1)
- Mental and Social Health (1)
- Molecular and Cellular Neuroscience (1)
- Neurology (1)
- Nursing (1)
- Other Mental and Social Health (1)
- Palliative Care (1)
- Palliative Nursing (1)
- Preventive Medicine (1)
- Psychiatric and Mental Health (1)
- Psychiatry and Psychology (1)
- Public Health (1)
- Publication
- Publication Type
Articles 1 - 2 of 2
Full-Text Articles in Neuroscience and Neurobiology
Alzheimer's And Patient Caregiver Burnout: A Review Of The Literature, Madeline Hekeler
Alzheimer's And Patient Caregiver Burnout: A Review Of The Literature, Madeline Hekeler
James Madison Undergraduate Research Journal (JMURJ)
The term “silent epidemic” is fitting for Alzheimer’s disease (AD), as its negative impact is widely felt but rarely discussed. Burnout among AD caregivers has become an epidemic of its own as caregivers experience an increase in health risks, stress, and financial burden. This literature review focuses on caregiver burnout and how imperative it is that caregivers are better supported in their role. Researchers have developed instruments to assess and intervene in caregiver burnout that have shown effectiveness among caregivers and their families.Nevertheless, further longitudinal research is warranted regarding more effective interventions, including stress management and social support mechanisms.
Characterizing Tau In The Nucleus, Shaw Grindle Camphire, Madeline Louise Henwood
Characterizing Tau In The Nucleus, Shaw Grindle Camphire, Madeline Louise Henwood
Senior Honors Projects, 2010-2019
A hallmark of Alzheimer’s Disease (AD) is the aggregation of hyperphosphorylated tau protein into neurofibrillary tangles. Tau localizes to both the cytoplasm and the nucleus of neuronal cells; however, its nuclear role has not been fully defined. Tau has recently been shown to bind to purine-pyrimidine (R/Y) repeats in DNA and stabilize them into Z-DNA. Evidence from our lab suggests that the binding of tau to R/Y repeats causes transcriptional changes of the NOS1 gene. Six major isoforms of tau exist in neurons. These isoforms fall into two groups, denoted as 3R tau and 4R tau, and are found at …