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Full-Text Articles in Neuroscience and Neurobiology
The Effects Of Long-Term Treadmill Exercise Training On Amyloid-Beta Plaque Levels And Behavioral Profile In 15-Month Tg2576 Mice, Riya R. Thomas
The Effects Of Long-Term Treadmill Exercise Training On Amyloid-Beta Plaque Levels And Behavioral Profile In 15-Month Tg2576 Mice, Riya R. Thomas
MSU Graduate Theses
Alzheimer’s disease (AD) is a progressive, neurodegenerative disease that is characterized by progressive loss of memory and cognitive function. The causative factors of this disease include modifications in neuronal cell metabolism, such as the progression of neurotic injury by amyloid beta (Aβ), and tau tangle deposition in the brain. Recent studies show that brain atrophy and other pathologic conditions are responsible for dementia in older individuals (80 years of age or older). Non-pharmacological interventions may have a role in both the prevention and slowing disease progression in AD. The role of exercise training in disease prevention has been evaluated in …