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Full-Text Articles in Neuroscience and Neurobiology

Utilizing Ai Integrated Neuroimaging Technology To Expand Upon Machine Learning In Positron Emission Tomography Technology With The Aim Of Detecting Amyloid Beta Biomarkers Early In The Onset Of Alzheimer's., Ethan S. Terman Jan 2024

Utilizing Ai Integrated Neuroimaging Technology To Expand Upon Machine Learning In Positron Emission Tomography Technology With The Aim Of Detecting Amyloid Beta Biomarkers Early In The Onset Of Alzheimer's., Ethan S. Terman

Undergraduate Research Posters

Early intervention in Alzheimer's is vital for treatment. The earlier a professional can detect symptoms and make a diagnosis the earlier a prognosis can be implemented. With the prevalence of data in our day-to-day world combined with Artificial intelligence (AI), utilizing both for machine learning can pave the way for more accurate and efficient detection of Alzheimer's and other neurodegenerative diseases. AI combined with Machine learning (ML) increases diagnostic efficiency and reduces human errors, making it a valuable resource for physicians and clinicians alike. With the increasing amount of data processing and image interpretation required, the ability to use AI …


Multilingualism And Memory: Investigating Possible Differences In The Abilities Of Monolingual And Multilingual College Students, Clara E. Barned Dec 2022

Multilingualism And Memory: Investigating Possible Differences In The Abilities Of Monolingual And Multilingual College Students, Clara E. Barned

Honors Projects

This study investigated whether there is a difference in the memories of monolingual and multilingual undergraduate students using simple memorization tasks. There were 46 participants, 30 of which were monolingual (only knew one language) and 16 of which were multilingual (knew two or more languages). There was found to be no significant difference between the performance of the two groups, with the data generating a p-value of 0.557. This study further suggests related avenues of research and ways in which the study could be improved in the future.


Effects Of Music Exposure On Autobiographical Memory In Alzheimer's Patients: A Systematic Review And Meta-Analysis, Gregory Vance May 2022

Effects Of Music Exposure On Autobiographical Memory In Alzheimer's Patients: A Systematic Review And Meta-Analysis, Gregory Vance

Honors Theses

The progression of Alzheimer’s disease is primarily characterized by a loss of memory concerning past events, as well as a lack in ability to create new memories. While this spans across many subsets of memory, such as recognition, recall, and autobiographical memory, there seems to be a lesser impact on musical memory in those with Alzheimer’s. Multiple studies have suggested that exposure to music and introduction of music therapy can even improve other aspects of memory in Alzheimer’s patients. This systematic review and meta-analysis sought to examine the relationship between music exposure and autobiographical memory specifically. A pool of electronic …


Regaining Effort-Based Food Motivation: The Drug Methylphenidate Reverses The Depressive Effects Of Tetrabenazine In Female Rats, Deanna Pietrorazio May 2022

Regaining Effort-Based Food Motivation: The Drug Methylphenidate Reverses The Depressive Effects Of Tetrabenazine In Female Rats, Deanna Pietrorazio

Honors Scholar Theses

Tetrabenazine (TBZ), a vesicular monoamine transporter type 2 (VMAT-2) inhibitor, depletes dopamine and induces motivational deficits and other depressive symptoms in humans. Methylphenidate (MPH) is a dopamine transport blocker that is used to enhance motivational function. Previous studies have shown that in male rats, TBZ induces a shift in effort-related choice such that a low-effort bias is induced. In male rats this occurs at a dose range of 0.75-1.0 mg/kg TBZ, and this effect is reversible with co-administration of MPH. Recent studies have shown that females need a higher dose of TBZ (2.0 mg/kg) to show the low-effort bias. The …


A Psychopharmacology Review Of Brexpiprazole, Nicole A. Marion Apr 2022

A Psychopharmacology Review Of Brexpiprazole, Nicole A. Marion

Conspectus Borealis

Brexpiprazole is an antipsychotic drug often used to help treat schizophrenia and major depressive disorder. This review paper breaks down the drugs history including what it is used for, how it is used, and how it was developed. Pharmacokinetics including administration routes, steady states, and metabolism. This review also describes pharmacodynamics, focusing on drug affinity. It will also discuss pharmacological effects pulling evidence from clinical trials. Last this review will describe the toxicology and safety of brexpiprazole.


Christianity And Fear: The Neuropsychological Processes Involved In The Relationship Between Fear And Religion, Courtney Welch-Horstman Jul 2021

Christianity And Fear: The Neuropsychological Processes Involved In The Relationship Between Fear And Religion, Courtney Welch-Horstman

Obsculta

Religion frames the lives and minds of individuals who practice the Christian faith. Regarding the mind, this statement can be understood both figuratively and literally. The thought processes of human beings who claim to believe in God are strongly influenced by their perspective of Deity and what they think God's primary characteristic is. While some view God as loving, others view God as mainly angry and punishing. The way this question is answered by an individual reveals much about his or her neurocircuitry and which brain structures are most active and developed. These circuits and structures then impact the behaviors …


Eeg Study Of The Featural And Configural Components Of Face Perception, Heather Rose Stegman Jan 2017

Eeg Study Of The Featural And Configural Components Of Face Perception, Heather Rose Stegman

Summer Research

Prior research using functional magnetic resonance imaging (fMRI) suggests that facial features (i.e. eyes, nose, and mouth) and their configuration (i.e. T-shaped arrangement of features) are processed in different face-specific brain regions. However, precise response time of featural and configural face processing is unknown. Featural processing may occur before configural processing, or configural processing may occur before featural processing; conversely, they may occur simultaneously. Here, using the electroencephalography (EEG), we will examine the face-specific event related potential (ERP), the N170, to analyze temporal differences between featural and configural face processing.


The Pribram – Bohm Hypothesis Part Ii: The Physiology Of Consciousness, Shelli R. Joye Sep 2016

The Pribram – Bohm Hypothesis Part Ii: The Physiology Of Consciousness, Shelli R. Joye

CONSCIOUSNESS: Ideas and Research for the Twenty-First Century

A physiology of consciousness is elaborated, based upon implications of the Pribram-Bohm hypothesis (developed in Part I of this series). The model presented here is in sharp contrast to the prevailing conviction among neuroscientists that consciousness will eventually be discovered to be a physiological epiphenomenon of neuronal electrical impulses firing in the brain. In contrast, the Pribram-Bohm theory holds that consciousness, inherent in what Bohm views cosmologically as “the Whole,” manifests as a dynamic conscious energy resonance bridging the explicate space-time domain with the nonlocal, transcendent flux domain termed the “implicate order.” Presented in Part I, the Pribram-Bohm hypothesis posits …


Norepinephrine Involvement In The Intermittent Swim Stress-Induced Deficit In Spatial Learning And Memory, Emily Elgert Apr 2013

Norepinephrine Involvement In The Intermittent Swim Stress-Induced Deficit In Spatial Learning And Memory, Emily Elgert

Honors Theses and Capstones

Learning and memory impairments are often caused by stress disorders including depression. The present study investigated the involvement of norepinephrine in the swim stress-induced deficits of spatial learning and memory. Exposure to intermittent swim stress (ISS) followed by learning and memory tests in the Morris water maze (MWM) were used to investigate this relationship. The ISS paradigm consists of intermittent exposure to cold water, producing stress responses in rats. Reboxetine, a norepinephrine selective reuptake inhibitor (NSRI), was employed to investigate whether this compound reverses the ISS-induced deficit. In other words, rats exposed to the ISS, were hypothesized to experience impaired …


Detecting Structure In Glass Patterns: An Interocular Transfer Study, Dawn Vreven, Jarrod Berge Dec 2012

Detecting Structure In Glass Patterns: An Interocular Transfer Study, Dawn Vreven, Jarrod Berge

Dawn L Vreven

Glass patterns are visual stimuli used here to study how local orientation signals are spatially integrated into global pattern perception. We measured a form aftereffect from adaptation to both static and dynamic Glass patterns and calculated the amount of interocular transfer to determine the binocularity of the detectors responsible for the perception of global structure. Both static and dynamic adaptation produced significant form aftereffects and showed a very high degree of interocular transfer, suggesting that Glass-pattern perception involves cortical processing beyond primary visual cortex. Surprisingly, dynamic adaptation produced significantly greater interocular transfer than static adaptation. Our results suggest a functional …


Genetics And Criminal Responsibility, Stephen J. Morse Jul 2011

Genetics And Criminal Responsibility, Stephen J. Morse

All Faculty Scholarship

Some believe that genetics threatens privacy and autonomy and will eviscerate the concept of human nature. Despite the astonishing research advances, however, none of these dire predictions and no radical transformation of the law have occurred.