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Neuroscience and Neurobiology Commons

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Psychiatry and Psychology

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Full-Text Articles in Neuroscience and Neurobiology

The Effects Of Prenatal Cannabis Exposure On The Basolateral Amygdala, Karen Kw Wong Aug 2022

The Effects Of Prenatal Cannabis Exposure On The Basolateral Amygdala, Karen Kw Wong

Undergraduate Student Research Internships Conference

Clinical and preclinical studies indicate prenatal cannabis exposure (PCE) pathologically affects fetal brain development and may increase vulnerability to neuropsychiatric disorders, including schizophrenia and mood/anxiety disorders. In review research from our lab suggests that fetal exposure to Δ9-THC sex-selectively impairs mesocorticolimbic (MCL) circuit function. However, there is a distinct lack of focus on PCE models on the BLA. The BLA plays a central role within the MCL where it directly interacts with the VTA, PFC and HIPP. Importantly, our model exhibits significant VTA hyperdopaminergic activity, and sex-specific alterations to PFC/HIPP glutamate firing, alongside region- and sex-specific changes in dopamine (DA), …


Multisensory Integration And Autistic Traits Using Non-Sociolinguistic Information, Sébastien A. Lauzon, Samantha E. Schulz, Zack I. Cohen, Ryan A. Stevenson Mar 2018

Multisensory Integration And Autistic Traits Using Non-Sociolinguistic Information, Sébastien A. Lauzon, Samantha E. Schulz, Zack I. Cohen, Ryan A. Stevenson

Western Research Forum

Background: Sensory processing issues are one of the most common complaints in autism spectrum disorder (ASD). One area of sensory difficulties in ASD that has been the focus of intense research in recent years is multisensory integration (MSI), or the ability to bind auditory and visual information into a single, unified percept. While integration of social or linguistic information is consistently shown to be an area of difficulty in ASD, results are less clear with simple, non-sociolinguistic stimuli. This study aims to address this ambiguity by determining whether MSI of non-sociolinguistic sensory information is related to traits and symptomatology …