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Dorsoventral Boundary For Organizing Growth And Planar Polarity In The Drosophila Eye, Amit Singh, Janghoo Lim, Kwang-Wook Choi

Amit Singh

A fundamental feature of developing tissues and organs is generation of planar polarity of cells in an epithelium with respect to the body axis.

The Drosophila compound eye shows two-tier dorsoventral (DV) planar polarity. At the individual ommatidium level, the eight photoreceptors in each unit eye form a dorsoventrally asymmetric cluster. At the level of eye field, hundreds of ommatidia in the upper and lower halves of an eye are uniformly polarized dorsally or ventrally, respectively. This results in DV mirror symmetries about the equator. The uniform orientations of photoreceptor clusters over long distance in the eye field provide an …