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Characterization Of Genes And Pathways Controlling Biofilm Formation In Saccharomyces Cerevisiae, Neha Sarode

Doctoral Dissertations

Biofilms are a mode of growth where aggregated cells adhere to a foreign surface and grow as a complex community. Biofilms have found wide utility in commercial industries, however infections caused by biofilms in clinical settings are a major cause of concern. Understanding molecular details of biofilm formation could help in exploitation or elimination efforts.

We utilize Saccharomyces cerevisiae as a model system to study biofilm formation. S. cerevisiae strain belonging to genetic background Σ [sigma] 1278b is capable of forming biofilms, on low density (0.3%) agar media. When grown at 25°[degree] C for 5 days, it develops into an …