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Laboratory and Basic Science Research Commons

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WellBeing International

Animal Experimentation and Research

Laboratory animals

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Full-Text Articles in Laboratory and Basic Science Research

Estimates For Worldwide Laboratory Animal Use In 2005, Katy Taylor, Nicky Gordon, Gill Langley, Wendy Higgins Jul 2008

Estimates For Worldwide Laboratory Animal Use In 2005, Katy Taylor, Nicky Gordon, Gill Langley, Wendy Higgins

Laboratory Experiments Collection

Animal experimentation continues to generate public and political concern worldwide. Relatively few countries collate and publish animal use statistics, yet this is a first and essential step toward public accountability and an informed debate, as well as being important for effective policy-making and regulation. The implementation of the Three Rs (replacement, reduction and refinement of animal experiments) should be expected to result in a decline in animal use, but without regular, accurate statistics, this cannot be monitored. Recent estimates of worldwide annual laboratory animal use are imprecise and unsubstantiated, ranging from 28–100 million. We collated data for 37 countries that …


Ethics, Welfare, And Laboratory Animal Management, David J. Allan, Judith K. Blackshaw Jan 1986

Ethics, Welfare, And Laboratory Animal Management, David J. Allan, Judith K. Blackshaw

Experimentation Collection

Animals have been used in medical research from as far back as 129-199 A.D. when Galen, a Greek medical scientist, used a pig for his experiments. In the sixteenth and seventeenth centuries, anatomical dissections were carried out on animals; Galvani used frogs in 1791 for his experiments and the Russian physiologist, Pavlov, carried out his famous dog experiments in the early 1900s. Since this time, large numbers of animals have been used in biomedical and other research. In 1963 the first edition of "The Guide for the Care and Use of Laboratory Animals" was published, and the United States Public …


Some Thoughts On The Laboratory Cage Design Process, Margaret E. Wallace Jan 1982

Some Thoughts On The Laboratory Cage Design Process, Margaret E. Wallace

Laboratory Experiments Collection

A block to progress in the design of cages and other restricted environments for animals has been the notion that animal and human needs are necessarily in conflict. The process of design should list the established and suspected animal needs separately from a list of human needs- husbandry and experimental. Comparison of the two lists will often show up more compatible needs than expected, and design features can be worked out to fulfill them. Adjustments may then be made where needs are less compatible until "sufficient" compatibility is achieved. An innovative design for a mouse cage is described, to show …


Lab Animal Housing: Numbers Or Common Sense?, Andrew N. Rowan Jan 1981

Lab Animal Housing: Numbers Or Common Sense?, Andrew N. Rowan

Laboratory Experiments Collection

No abstract provided.