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Laboratory and Basic Science Research Commons™
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Full-Text Articles in Laboratory and Basic Science Research
Ethics, Welfare, And Laboratory Animal Management, David J. Allan, Judith K. Blackshaw
Ethics, Welfare, And Laboratory Animal Management, David J. Allan, Judith K. Blackshaw
Experimentation Collection
Animals have been used in medical research from as far back as 129-199 A.D. when Galen, a Greek medical scientist, used a pig for his experiments. In the sixteenth and seventeenth centuries, anatomical dissections were carried out on animals; Galvani used frogs in 1791 for his experiments and the Russian physiologist, Pavlov, carried out his famous dog experiments in the early 1900s. Since this time, large numbers of animals have been used in biomedical and other research. In 1963 the first edition of "The Guide for the Care and Use of Laboratory Animals" was published, and the United States Public …
The Imbalance Between Experiment And Theory In Biology: The Need For Theory-Directed Modeling, M. L. Fidelman, D. C. Mikulecky
The Imbalance Between Experiment And Theory In Biology: The Need For Theory-Directed Modeling, M. L. Fidelman, D. C. Mikulecky
Experimentation Collection
In biological and biomedical research, the vast majority of resources are focused on conducting experiments. Most of these experiments utilize animals. Only a tiny amount of resources is spent on theory and modeling. It is our contention and the basic theme of this paper that the imbalance between theory and experiment in biology produces very poor science. The implications of which are that many of the experiments conducted have little real scientific meaning or value and, therefore, go hand-in-hand with unnecessary animal use and suffering. Given the finite resources available for research, the redirection of significant resources from an almost …