Laboratory and Basic Science Research Commons^™

Anatomical Organization And Distinction Of The Sympathetic Inputs To Interscapular Brown Adipose Tissue And Inguinal White Adipose Tissue In The Mouse, Clara Jane Huesing

LSU Doctoral Dissertations

Adipose tissue is a dynamic endocrine organ that contains both the problem and the solution to discovering new therapies for individuals with obesity. Excessive adipose tissue disrupts energy balance and causes a host of comorbidities like insulin resistance and hypertension. On the other hand, adipose tissue is essential for life. During periods of energy demand, sympathetic nerve activity in brown and white adipose tissue stimulates thermogenesis and lipolysis; both of which decrease body weight and improve metabolic health. Therefore, comprehensive insight into the organization of sympathetic innervation and how it communicates with adipocytes is critical in order to utilize its …