Kinesiology Commons^™

Exercise-Induced Alterations In Melanocortin Receptor Expression And Inflammation, Tara Michelle Henagan

LSU Doctoral Dissertations

Inflammatory cytokines play a significant role in the pathogenesis of obesity-related diseases and have been implicated as integral factors in both early and late phases of atherosclerosis. Lifestyle modifications such as increasing physical activity and making dietary changes to induce weight loss are part of the primary prescription for the treatment of metabolic syndrome. Additionally, physical activity has been implicated as a potentially effective regimen for the control of inflammation, yet little is known about the anti-inflammatory mechanistic alterations induced by physical activity.

Exercise training causes acute changes in inflammation immediately post exercise, evidenced by upregulation of inflammatory cytokines and …

Effects Of High-Load Eccentric Exercise Training On Rat Soleus Muscle Myofibrillar Disruption Following One-Week Of Hindlimb Suspension Unloading And Subsequent Reloading, Rhonda Dianne Prisby

LSU Doctoral Dissertations

Purpose: This investigation evaluated the effects of a high-load (50% body weight) eccentric exercise training protocol on reloading myofibrillar damage in soleus (SOL) and extensor digitorum longus (EDL) muscles in rats following 7 days (d) of hindlimb suspension unloading (HSU). Methods: 48 female Sprague-Dawley rats were randomly stratified to four experimental groups; exercise + hindlimb suspension unloading (ExHSU), hindlimb suspension unloading (HSU), exercise (Ex) and control (C). The ExHSU and Ex groups underwent a high-load eccentric exercise protocol for ~2.5 weeks. Following exercise training, the ExHSU and HSU groups underwent 7 d of hindlimb suspension unloading and a subsequent 16-19 …