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The Immediate And Extended Effect Of Diet And Exercise On Metabolic Flexibility, Timothy Allerton
The Immediate And Extended Effect Of Diet And Exercise On Metabolic Flexibility, Timothy Allerton
LSU Doctoral Dissertations
Metabolic inflexibility is an emerging physiological marker indicative of metabolic dysfunction and associated with type 2 diabetes (T2D) and obesity. Exercise is a potent stimulus to improve metabolic health, however, not much is known about the acute effects of exercise on metabolic flexibility (METFLEX). The purpose of this dissertation was study the time-course of diet and exercise and its effects on METFLEX. Three studies were conducted to investigate molecular and clinical aspects of diet and exercise and how these stimuli may alter the metabolic response to fuel. The first study was conducted on obesity-prone, Osborne-Mendel (OM) and obesity-resistant S5B/Pl (S5B) …