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The Effect Of Aerobic Exercise Versus Inactivity On Nitric Oxide Concentration And Synthesis In An Elderly Population, Samantha Burton
The Effect Of Aerobic Exercise Versus Inactivity On Nitric Oxide Concentration And Synthesis In An Elderly Population, Samantha Burton
Theses and Dissertations
CONTEXT: Nitric Oxide (NO) is an endothelial-derived vasoactive molecule that causes an increase in blood flow and oxygen delivery to tissue. A reduction in NO bioavailability has been found to occur in adults over the age of 60 and can be reversed pharmacologically by improving NO synthase (NOS) activity. Reversing these age-related changes with alternative interventions, such as aerobic exercise, has shown some promising results. OBJECTIVE: To quantify blood NO-bioavailability (as measured by blood nitrite levels) in a population of aerobically trained elderly men and compare these data to a group of age-matched, inactive individuals. In addition, we measured the …