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Introducing A Novel Method For Genetic Analysis Of Autism Spectrum Disorder, Sepideh Nouri
Introducing A Novel Method For Genetic Analysis Of Autism Spectrum Disorder, Sepideh Nouri
Dissertations & Theses (Open Access)
Autism is a spectrum of neurological disorders that is characterized by repetitive and stereotyped behaviors, lack of social skills in verbal and non-verbal communications, and intellectual disability. Recent statistics shows that 1 out of every 88 children in the US is affected by autism.
In this thesis, I first review previous studies on genetic association analyses of autism spectrum disorder. A large number of these studies fall into two categories: Genome Wide Association Studies (GWAS) and sequencing studies. Although GWAS are able to identify multiple common risk variants associated with different diseases, these common variants explain only a small portion …