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Genetics and Genomics Commons

Open Access. Powered by Scholars. Published by Universities.®

2002

Bayesian inference

Articles 1 - 2 of 2

Full-Text Articles in Genetics and Genomics

Testing For Genetic Evidence Of Population Expansion And Contraction: An Empirical Analysis Of Microsatellite Dna Variation Using A Hierarchical Bayesian Model, Jay F. Storz, Mark Beaumont Aug 2002

Testing For Genetic Evidence Of Population Expansion And Contraction: An Empirical Analysis Of Microsatellite Dna Variation Using A Hierarchical Bayesian Model, Jay F. Storz, Mark Beaumont

Jay F. Storz Publications

The role of past climatic change in shaping the distributions of tropical rain forest vertebrates is central to long-standing hypotheses about the legacy of the Quaternary ice ages. One approach to testing such hypotheses is to use genetic data to infer the demographic history of codistributed species. Population genetic theory that relates the structure of allelic genealogies to historical changes in effective population size can be used to detect a past history of demographic expansion or contraction. The fruit bats Cynopterus sphinx and C. brachyotis (Chiroptera: Pteropodidae) exhibit markedly different distribution patterns across the Indomalayan region and therefore represent an …


Genetic Evidence For Long-Term Population Decline In A Savannah Dwelling Primate: Inferences From A Hierarchical Bayesian Model, Jay F. Storz, Mark A. Beaumont, Susan C. Alberts Jul 2002

Genetic Evidence For Long-Term Population Decline In A Savannah Dwelling Primate: Inferences From A Hierarchical Bayesian Model, Jay F. Storz, Mark A. Beaumont, Susan C. Alberts

Jay F. Storz Publications

The purpose of this study was to test for evidence that savannah baboons (Papio cynocephalus) underwent a population expansion in concert with a hypothesized expansion of African human and chimpanzee populations during the late Pleistocene. The rationale is that any type of environmental event sufficient to cause simultaneous population expansions in African humans and chimpanzees would also be expected to affect other codistributed mammals. To test for genetic evidence of population expansion or contraction, we performed a coalescent analysis of multilocus microsatellite data using a hierarchical Bayesian model. Markov chain Monte Carlo (MCMC) simulations were used to estimate …