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Full-Text Articles in Genetics and Genomics
Study Of Sickle Cell Disease, Aaron Guevarra, Carlos Herrera, Faysal Ali
Study Of Sickle Cell Disease, Aaron Guevarra, Carlos Herrera, Faysal Ali
Undergraduate Research Symposium Posters
The purpose of this research timeline is to explore the history, prevalence, and effects of Sickle Cell Disease (SCD) so that treatments and possible future experiments or cures may be discussed. In SCD, abnormal red blood cells appear as sickle shaped as opposed to the round shape of normal red blood cells. It is inherited in an autosomal recessive pattern, so an individual must inherit two copies of the allele. The gene mutation is a single nucleotide mutation in the gene which codes for β-globin. In 1910, James B. Herrick first described the disease, and in 1949, its inheritance pattern …