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Articles 1 - 6 of 6
Full-Text Articles in Genetics and Genomics
Electrochemical Inactivation Of Tobacco Mosaic Virus: A Novel Vaccine Method, Angelica Diaz
Electrochemical Inactivation Of Tobacco Mosaic Virus: A Novel Vaccine Method, Angelica Diaz
Undergraduate Research Symposium Posters
We tested the effectiveness of using electrochemistry to irreversibly damage Tobacco Mosaic Virus (TMV). Hypothesis: By utilizing the acidic properties of DNA and RNA, viral genetic material can be irreversibly and selectively damaged using electrochemical methods. Technique could assist in development of highly targeted and effective vaccines.
Study Of Sickle Cell Disease, Aaron Guevarra, Carlos Herrera, Faysal Ali
Study Of Sickle Cell Disease, Aaron Guevarra, Carlos Herrera, Faysal Ali
Undergraduate Research Symposium Posters
The purpose of this research timeline is to explore the history, prevalence, and effects of Sickle Cell Disease (SCD) so that treatments and possible future experiments or cures may be discussed. In SCD, abnormal red blood cells appear as sickle shaped as opposed to the round shape of normal red blood cells. It is inherited in an autosomal recessive pattern, so an individual must inherit two copies of the allele. The gene mutation is a single nucleotide mutation in the gene which codes for β-globin. In 1910, James B. Herrick first described the disease, and in 1949, its inheritance pattern …
The History And Future Of Cystic Fibrosis, Randall Combs, Che Fung Andy Chan, Daisy Sahagun
The History And Future Of Cystic Fibrosis, Randall Combs, Che Fung Andy Chan, Daisy Sahagun
Undergraduate Research Symposium Posters
The purpose of this research timeline is to highlight the tumultuous yet inspiring history of Cystic Fibrosis disease and treatment to give us a more pragmatic understanding of its current state. Cystic Fibrosis is an autosomal recessive disease, most often caused by a single amino-acid deletion of phenylalanine at position 508 in the nucleotide binding domain, which results in a loss of the cystic fibrosis transmembrane conductance regulator (CFTR). Symptomatology varies considerably but a buildup of mucus in the respiratory tract leading to lung failure, and exocrine pancreatic insufficiency which results in digestive and metabolic dysfunction are commonly, if not …
A Timeline Of Oculocutaneous Albinism, Mohammed Abushanab, Maria Ceroni, Kimberly Morán
A Timeline Of Oculocutaneous Albinism, Mohammed Abushanab, Maria Ceroni, Kimberly Morán
Undergraduate Research Symposium Posters
The purpose of this research timeline is to synthesize the natural history of Oculocutaneous Albinism (OCA), discover gaps in knowledge, as well as understand the genes and mutations that incite the disease. It is through methods of literature-based research that we found the earliest recognition of OCA and investigated it up to its most current state of research. The rate of research remains steady and continuous with the focus varying widely; either by examining more of the genes involved in the disease or by taking more in-depth looks at mutational analyses of genes that are already observed to be linked …
An Investigation On The History And Current Research Of Fragile X Syndrome, Makeda Asare, Isabelle Avenido, Maxene Vergonia-Fehlman
An Investigation On The History And Current Research Of Fragile X Syndrome, Makeda Asare, Isabelle Avenido, Maxene Vergonia-Fehlman
Undergraduate Research Symposium Posters
The purpose of this research is to synthesize the history of Fragile X Syndrome through literature-based research in order to assess the scope of research, population variation, social impact, and treatment. Fragile X was first documented in 1943 by Dr. Julia Bell and Dr. James Purdon Martin in a report of a family case study in which eleven males across two generations showed symptoms of intellectual disabilities. Fragile X Syndrome is an X-linked disorder caused by mutation in the Fragile X mental retardation 1(FMR1) gene on chromosome Xq27.3. The FMR1 mutations are triplet repeat expansion of the CGG repeat sequences …
Retinoblastoma: Past, Present, And Future, Izabela Daneva, Crysty-Ann Olaco, Albert Tran
Retinoblastoma: Past, Present, And Future, Izabela Daneva, Crysty-Ann Olaco, Albert Tran
Undergraduate Research Symposium Posters
The purpose of this research timeline is to synthesize the natural history of retinoblastoma to understand its societal effects and develop a public health message to raise awareness of the disease. We used literature-based research in order to gain an understanding about the discovery of this disease and investigate its most current state of knowledge. Retinoblastoma is an intraocular cancer that manifests early in childhood. It is typically linked to a somatic or germline insertion, deletion, or single-base substitution mutation on both alleles of RB1, a tumor-suppressor gene. Retinoblastoma was first identified in 1809 by James Wardrop, and since then, …