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Full-Text Articles in Genetics and Genomics
Disruption Of Rna Metabolism By Zika Virus, Maggie Lea Dickerson
Disruption Of Rna Metabolism By Zika Virus, Maggie Lea Dickerson
Honors Theses
Flaviviruses are positive, single-stranded, enveloped RNA viruses that are a part of the family, Flaviviridae. West Nile virus, Dengue, Zika virus and more are a part of this family. Mosquitoes are the vectors for these viruses. In order for the virus to infect mosquitoes, it must evade the RNA interference (RNAi), which is the major antiviral immune mechanism of insects. One study found the 3’ untranslated region (UTR) of the West Nile virus that inhibited the RNAi (GP et al. 2016). The goal of this study is to investigate if the 3’ and 5’ UTR region of the Zika virus …
The Characterization Of The Transcription Factor Msab And Its Role In Staphylococcal Virulence, Justin Batte
The Characterization Of The Transcription Factor Msab And Its Role In Staphylococcal Virulence, Justin Batte
Dissertations
Staphylococcus aureus is a common human pathogen that is responsible for a wide range of infections, ranging from relative minor skin infections to life-threatening disease such as bacteremia, septicemia, and endocarditis. S. aureus possesses many different virulent factors that aid in its ability to cause this wide array of infections. One major virulence factor includes the production of capsular polysaccharide (CP). The production of CP plays a major role in the virulence response during infection specifically by providing S. aureus an antiphagocytic mechanism that allows the pathogen to evade phagocytosis during an infection. S. aureus has developed complex genetic regulatory …
Genetic Homogeneity Of The Invasive Lionfish Across The Northwestern Atlantic And The Gulf Of Mexico Based On Single Nucleotide Polymorphisms, R. Pérez-Portela, A. Bumford, B. Coffman, S. Wedelich, M. Davenport, Alex Fogg, M.K. Swenarton, F. Coleman, M.A. Johnston, D.L. Crawford, M.F. Oleksiak
Genetic Homogeneity Of The Invasive Lionfish Across The Northwestern Atlantic And The Gulf Of Mexico Based On Single Nucleotide Polymorphisms, R. Pérez-Portela, A. Bumford, B. Coffman, S. Wedelich, M. Davenport, Alex Fogg, M.K. Swenarton, F. Coleman, M.A. Johnston, D.L. Crawford, M.F. Oleksiak
Student Publications
Despite the devastating impact of the lionfish (Pterois volitans) invasion on NW Atlantic ecosystems, little genetic information about the invasion process is available. We applied Genotyping by Sequencing techniques to identify 1,220 single nucleotide polymorphic sites (SNPs) from 162 lionfish samples collected between 2013 and 2015 from two areas chronologically identified as the first and last invaded areas in US waters: the east coast of Florida and the Gulf of Mexico. We used population genomic analyses, including phylogenetic reconstruction, Bayesian clustering, genetic distances, Discriminant Analyses of Principal Components, and coalescence simulations for detection of outlier SNPs, to understand …