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Processes On The Emergent Landscapes Of Biochemical Reaction Networks And Heterogeneous Cell Population Dynamics: Differentiation In Living Matters., Sui Huang, Fangting Li, Joseph X Zhou, Hong Qian

Articles, Abstracts, and Reports

The notion of an attractor has been widely employed in thinking about the nonlinear dynamics of organisms and biological phenomena as systems and as processes. The notion of a landscape with valleys and mountains encoding multiple attractors, however, has a rigorous foundation only for closed, thermodynamically non-driven, chemical systems, such as a protein. Recent advances in the theory of nonlinear stochastic dynamical systems and its applications to mesoscopic reaction networks, one reaction at a time, have provided a new basis for a landscape of open, driven biochemical reaction systems under sustained chemostat. The theory is equally applicable not only to …