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Genetics and Genomics Commons

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University of New Hampshire

Molecular, Cellular & Biomedical Sciences

2009

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Full-Text Articles in Genetics and Genomics

Insertion Sequence Content Reflects Genome Plasticity In Strains Of The Root Nodule Actinobacterium Frankia, Derek M. Bickhart, Johann P. Gogarten, Pascal Lapierre, Louis S. Tisa, Philippe Normand, David R. Benson Oct 2009

Insertion Sequence Content Reflects Genome Plasticity In Strains Of The Root Nodule Actinobacterium Frankia, Derek M. Bickhart, Johann P. Gogarten, Pascal Lapierre, Louis S. Tisa, Philippe Normand, David R. Benson

Molecular, Cellular & Biomedical Sciences

Background: Genome analysis of three Frankia sp. strains has revealed a high number of transposable elements in two of the strains. Twelve out of the 20 major families of bacterial Insertion Sequence (IS) elements are represented in the 148 annotated transposases of Frankia strain HFPCcI3 (CcI3) comprising 3% of its total coding sequences (CDS). EAN1pec (EAN) has 183 transposase ORFs from 13 IS families comprising 2.2% of its CDS. Strain ACN14a (ACN) differs significantly from the other strains with only 33 transposase ORFs (0.5% of the total CDS) from 9 IS families. Results: Insertion sequences in the Frankia genomes were …