Open Access. Powered by Scholars. Published by Universities.®
- Keyword
- Publication
- Publication Type
Articles 1 - 2 of 2
Full-Text Articles in Genetics and Genomics
Regulation Of Brown Adipocyte Gene Expression By The Histone 3 Lysine 4 Demethylase Kdm1b, Vy P. Tran
Regulation Of Brown Adipocyte Gene Expression By The Histone 3 Lysine 4 Demethylase Kdm1b, Vy P. Tran
Georgia State Undergraduate Research Conference
No abstract provided.
Integration Of Breast Cancer Gene Signatures Based On Graph Centrality, Jianxin Wang, Gang Chen, Min Li, Yi Pan
Integration Of Breast Cancer Gene Signatures Based On Graph Centrality, Jianxin Wang, Gang Chen, Min Li, Yi Pan
Computer Science Faculty Publications
Background: Various gene-expression signatures for breast cancer are available for the prediction of clinical outcome. However due to small overlap between different signatures, it is challenging to integrate existing disjoint signatures to provide a unified insight on the association between gene expression and clinical outcome.
Results: In this paper, we propose a method to integrate different breast cancer gene signatures by using graph centrality in a context-constrained protein interaction network (PIN). The context-constrained PIN for breast cancer is built by integrating complete PIN and various gene signatures reported in literatures. Then, we use graph centralities to quantify the importance of …