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- Assay (1)
- Biomarker (1)
- Bulky DNA adducts (1)
- Chromatin structure (1)
- Clustering (1)
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- Coke oven workers (1)
- Correlation (1)
- DNA fragmentation (1)
- DNA integrity (1)
- Endothelial cellular function (1)
- Feature selection (1)
- Gene expression patterns (1)
- Human fertility (1)
- Hydrocarbons (1)
- Inflammatory responses (1)
- P53 (1)
- Polycyclic aromatic (1)
- Polycyclic aromatic hydrocarbons (1)
- Projection targets (1)
- Semen quality (1)
- Solid phase extraction (1)
- Stress (1)
- Urinary (1)
- Visualization (1)
Articles 1 - 3 of 3
Full-Text Articles in Genetics and Genomics
P53: "The Wall Watcher", Nektarios Barabutis, John D. Catravas
P53: "The Wall Watcher", Nektarios Barabutis, John D. Catravas
Bioelectrics Publications
No abstract provided.
Global Analysis Of Gene Expression And Projection Target Correlations In The Mouse Brain, Ahmed Fakhry, Tao Zeng, Hanchuan Peng, Shuiwang Ji
Global Analysis Of Gene Expression And Projection Target Correlations In The Mouse Brain, Ahmed Fakhry, Tao Zeng, Hanchuan Peng, Shuiwang Ji
Computer Science Faculty Publications
Recent studies have shown that projection targets in the mouse neocortex are correlated with their gene expression patterns. However, a brain-wide quantitative analysis of the relationship between voxel genetic composition and their projection targets is lacking to date. Here we extended those studies to perform a global, integrative analysis of gene expression and projection target correlations in the mouse brain. By using the Allen Brain Atlas data, we analyzed the relationship between gene expression and projection targets. We first visualized and clustered the two data sets separately and showed that they both exhibit strong spatial autocorrelation. Building upon this initial …
Sperm Dna Oxidative Damage And Dna Adducts, Hueiwang Anna Jeng, Chih-Hong Pan, Mu-Rong Chao, Wen-Yi Lin
Sperm Dna Oxidative Damage And Dna Adducts, Hueiwang Anna Jeng, Chih-Hong Pan, Mu-Rong Chao, Wen-Yi Lin
Community & Environmental Health Faculty Publications
The objective of this study was to investigate DNA damage and adducts in sperm from coke oven workers who have been exposed to polycyclic aromatic hydrocarbons. A longitudinal study was conducted with repeated measurements during spermatogenesis. Coke-oven workers (n =112) from a coke-oven plant served the PAH-exposed group, while administrators and security personnel (n=67) served the control. Routine semen parameters (concentration, motility, vitality, and morphology) were analyzed simultaneously; the assessment of sperm DNA integrity endpoints included DNA fragmentation, bulky DNA adducts, and 8-oxo-7,8-dihydro-2'-deoxyguanosine (8-oxo-dGuo). The degree of sperm DNA fragmentation was measured using the terminal deoxynucleotidyl transferase-mediated dUTP nick end-labeling …