Open Access. Powered by Scholars. Published by Universities.®
- Keyword
-
- ATG-9 (1)
- Alfalfa (1)
- Astronomy (1)
- Autophagosome (1)
- Autophagy (1)
-
- Biology (1)
- Cancer (1)
- Co-extraction (1)
- Development (1)
- Endocytosis (1)
- Endosome (1)
- Evidence-Based (1)
- ExoR (1)
- Exoplanets (1)
- GTPase (1)
- Genetics (1)
- Germ layers (1)
- Invasion switch (1)
- Medicago sativa (1)
- Microbe interaction (1)
- Pluripotency (1)
- Protein (1)
- RAB-10 (1)
- S. meliloti (1)
- Science (1)
- T-box proteins (1)
- Touch DNA (1)
- Trypsin (1)
Articles 1 - 5 of 5
Full-Text Articles in Genetics and Genomics
Unseen Science: Modern Discoveries Too Far Away Or Tiny For Human Eyes, Lucy Huang
Unseen Science: Modern Discoveries Too Far Away Or Tiny For Human Eyes, Lucy Huang
Capstones
As science has progressed, scientists have realized that evidence goes beyond the realms of physical sight. Whether it is too small or difficult to find, scientists have developed different ways to get around this problem. We see this in cancer genomics and in extrasolar planetary research. Scientists use what they know and what they measure to validate their work.
https://lucy-huang-9tge.squarespace.com/
The Role Of T-Box Proteins In Vertebrate Germ Layer Formation And Patterning, Sushma Teegala
The Role Of T-Box Proteins In Vertebrate Germ Layer Formation And Patterning, Sushma Teegala
Dissertations, Theses, and Capstone Projects
All of the tissues in triploblastic organisms, with the exception of the germ cells, arise from the three germ layers, ectoderm, mesoderm and the endoderm. The identification of the genes that underlie the differentiation of these layers is crucial to our understanding of development. T-box family proteins are DNA-binding transcriptional regulators that play important roles during germ layer formation in the early vertebrate embryo. Well-characterized members of this family, including the transcriptional activators Brachyury and VegT, are essential for the proper formation of mesoderm and endoderm, respectively. To date, T-box proteins have not been shown to play a role in …
Optimizing A Method For Simultaneous Recovery Of Proteins And Dna From Fingerprints, Steven Kranes
Optimizing A Method For Simultaneous Recovery Of Proteins And Dna From Fingerprints, Steven Kranes
Student Theses
DNA testing on touched objects is a valuable tool in forensic investigations, but DNA is usually present in low amounts, causing poor STR typing results. For touch DNA evidence, there is a clear need for additional individualization, especially for highly probative samples. This could be achieved by testing genetically variable proteins. The goal of this project was to develop a DNA/protein co-extraction method to facilitate DNA and protein testing on the same evidence item. Existing DNA extraction methods were carefully adjusted to allow for downstream mass spectrometry analysis. Initial experiments on saliva and fingerprints placed on glass suggested that trypsin …
The Recycling Gtpase, Rab-10, Regulates Autophagy Flux In Caenorhabditis Elegans, Nicholas J. Palmisano
The Recycling Gtpase, Rab-10, Regulates Autophagy Flux In Caenorhabditis Elegans, Nicholas J. Palmisano
Dissertations, Theses, and Capstone Projects
Autophagy and endocytosis are two cellular pathways that are vital to cell growth and homeostasis. Autophagy is a dynamic and catabolic process involving the formation of a double-membrane vesicle called the autophagosome, which engulfs long-lived proteins and damaged organelles. Endocytosis involves the uptake of extracellular material into the cell through the formation of intracellular vesicles termed endosomes. Although both endocytosis and autophagy are interconnected processes, the extent to which endocytic proteins and/or compartments contribute to autophagy, and how these endocytic components do so, is still unknown. To improve our understanding of the connections that exist between autophagy and endocytosis, we …
Environmental Changes Turn On The Sinorhizobium Melitloti Exor-Exos/Chvi (Rsi) Host Invasion Switch, Shari N. Walcott
Environmental Changes Turn On The Sinorhizobium Melitloti Exor-Exos/Chvi (Rsi) Host Invasion Switch, Shari N. Walcott
Dissertations, Theses, and Capstone Projects
The free-living Gram-negative soil bacterium, Sinorhizobium meliloti, must switch into its host-invading form in order to infect the root hairs of the host plant, alfalfa (Medicago sativa), and establish a nitrogen-fixing symbiosis. The activation of the switch is believed to occur inside the infection chamber that is formed by curling of the root hairs. It is not fully understood what signals in the environment of the root hairs trigger and infection chamber S. meliloti to switch into a host-invading form since these signals were not extensively examined until now. This switch can be observed directly, due to …