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Genome-Wide Association Study Of Infectious Bovine Keratoconjunctivitis In Angus Cattle, Kadir Kizilkaya, Richard G. Tait Jr., Dorian J. Garrick, Rohan L. Fernando, James M. Reecy

Richard G. Tait Jr.

Background Infectious Bovine Keratoconjunctivitis (IBK) in beef cattle, commonly known as pinkeye, is a bacterial disease caused by Moraxella bovis. IBK is characterized by excessive tearing and ulceration of the cornea. Perforation of the cornea may also occur in severe cases. IBK is considered the most important ocular disease in cattle production, due to the decreased growth performance of infected individuals and its subsequent economic effects. IBK is an economically important, lowly heritable categorical disease trait. Mass selection of unaffected animals has not been successful at reducing disease incidence. Genome-wide studies can determine chromosomal regions associated with IBK susceptibility. The …