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Genetics and Genomics Commons

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Full-Text Articles in Genetics and Genomics

Connecting Through Consilience: Ecology, Society, Culture And Technology, Ruth Mirams, Alexander Hayes Jul 2014

Connecting Through Consilience: Ecology, Society, Culture And Technology, Ruth Mirams, Alexander Hayes

Alexander Hayes Mr.

Amongst linguistic, cultural and geographic diversity, humanity is characterised by inquisitiveness, communication and a deep desire to connect with each other. Despite our advanced intelligence and technological capacity, we are creatures of nature - a species which occupies a habitat, depends on consumable resources and fragile in many ways. As a species, we currently face challenges including overpopulation, diminishing resources and habitat degradation. In essence, we are exhausting the resources we depend on. [1] Resource depletion, disruption, famine, growth and sustainability are all observable in other species and natural systems. Human societies and systems can be described through the same …


Differential Expression Of Cyclin G2, Cyclin Dependent Kinase Inhibitor 2c And Peripheral Myelin Protein 22 Genes During Adipogenesis..Pdf, Jibin Zhang, Yeunsu Suh, Young Min Choi, Jinsoo Ahn, Michael E. Davis, Kichoon Lee May 2014

Differential Expression Of Cyclin G2, Cyclin Dependent Kinase Inhibitor 2c And Peripheral Myelin Protein 22 Genes During Adipogenesis..Pdf, Jibin Zhang, Yeunsu Suh, Young Min Choi, Jinsoo Ahn, Michael E. Davis, Kichoon Lee

Jibin Zhang

Increase of fat cells (FCs) in adipose tissue is attributed to proliferation of preadipocytes or immature adipocytes in the early stage, as well as adipogenic differentiation in the later stage of adipose development. Although both events are involved in the FC increase, they are contrary to each other, because the former requires cell cycle activity, whereas the latter requires cell cycle withdrawal. Therefore, appropriate regulation of cell cycle inhibition is critical to adipogenesis. In order to explore the important cell cycle inhibitors and study their expression in adipogenesis, we adopted a strategy combining the Gene Expression Omnibus (GEO) database available …


Jibin Zhang's Ppt For Midwest Meeting.Pdf, Jibin Zhang, Yeunsu Suh, Young Min Choi, Michael E. Davis, Kichoon Lee Mar 2014

Jibin Zhang's Ppt For Midwest Meeting.Pdf, Jibin Zhang, Yeunsu Suh, Young Min Choi, Michael E. Davis, Kichoon Lee

Jibin Zhang

Increasing numbers of fat cells in adipose tissue are attributed to proliferation of preadipocytes or immature adipocytes in the early stages as well as adipogenic differentiation in the later stages of adipogenesis. Although both events are involved in the increase in fat cell numbers, they are contrary to each other in that the former requires cell cycle activity whereas the latter requires cell cycle withdrawal. Therefore, appropriate regulation of cell cycle inhibition is critical to adipogenesis.
To explore the important cell cycle inhibitors and study their expression in adipogenesis, a strategy was adopted that combined the Gene Expression Omnibus (GEO) …


A Comprehensive Microrna Expression Profile Of The Backfat Tissue From Castrated And Intact Full-Sib Pair Male Pigs.Pdf, Ying Bai, Jinming Huang, Gang Liu, Jibin Zhang, Jianying Wang, Chengkun Liu, Meiying Fang Jan 2014

A Comprehensive Microrna Expression Profile Of The Backfat Tissue From Castrated And Intact Full-Sib Pair Male Pigs.Pdf, Ying Bai, Jinming Huang, Gang Liu, Jibin Zhang, Jianying Wang, Chengkun Liu, Meiying Fang

Jibin Zhang

Background: It is widely known that castration has a significant effect on the accumulation of adipose tissue. microRNAs (miRNAs) are known to be involved in fat deposition and to be regulated by the androgen-induced androgen receptor (AR). However, there is little understanding of the relationship between miRNAs and fat deposition after castration. In this study, the high-throughput SOLiD sequencing approach was used to identify and characterize miRNA expression in backfat from intact and castrated full-sib male 23-week-old pigs. The patterns of adipogenesis and fat deposition were compared between castrated and intact male pigs.
Results: A total of 366 unique miRNA …


Selection And Phenotypic Characterization Of A Core Collection Of Brachypodium Distachyon Inbred Lines, Ludmilla Tyler, Johnathan U. Fangel, Alexandra D. Fagerström, Michael A. Steinwand, Ted K. Raab, William Gt Willats, John P. Vogel Jan 2014

Selection And Phenotypic Characterization Of A Core Collection Of Brachypodium Distachyon Inbred Lines, Ludmilla Tyler, Johnathan U. Fangel, Alexandra D. Fagerström, Michael A. Steinwand, Ted K. Raab, William Gt Willats, John P. Vogel

Ted K. Raab

The model grass Brachypodium distachyon is increasingly used to study various aspects of grass biology. A large and genotypically diverse collection of B. distachyon germplasm has been assembled by the research community. The natural variation in this collection can serve as a powerful experimental tool for many areas of inquiry, including investigating biomass traits. We surveyed the phenotypic diversity in a large collection of inbred lines and then selected a core collection of lines for more detailed analysis with an emphasis on traits relevant to the use of grasses as biofuel and grain crops. Phenotypic characters examined included plant height, …


Pearl Millet Breeding Lines Developed At Icrisat:A Reservoir Of Variability And Useful Source, Mahalingam Govindaraj Jan 2014

Pearl Millet Breeding Lines Developed At Icrisat:A Reservoir Of Variability And Useful Source, Mahalingam Govindaraj

Mahalingam Govindaraj

The International Crops Research Institute for the Semi- Arid Tropics (ICRISAT) conducts inter-disciplinary and partnership-based research for the genetic improvement of its mandate crops. During the 1970s and 1980s, the pearl millet improvement at ICRISAT, Patancheru, emphasized on: (i) developing a diverse range of traitspecific composites, based on the germplasm largely from the Western and Central Africa; (ii) improving them by the process of recurrent selection, principally for grain yield and downy mildew (Sclerospora graminicola (Sacc.) Schroet ) resistance; and (iii) developing open-pollinated varieties (OPVs)