Entomology Commons^™

Natural Hyperthermia And Expression Of The Heat Shock Protein Hsp70 Affect Developmental Abnormalities In Drosophila Melanogaster, Stephen P. Roberts, Martin E. Feder

Biological Sciences Faculty Research & Creative Works

We Demonstrate that Natural Heat Stress on Wild Larval Drosophila Melanogaster Results in Severe Developmental Defects in >10% of Eclosing Adults, and that Increased Copy Number of the Gene Encoding the Major Inducible Heat Shock Protein of D. Melanogaster, Hsp70, is Sufficient to Reduce the Incidence of Such Abnormalities. Specifically, Non-Adult D. Melanogaster Inhabiting Necrotic Fruit Experienced Severe, Often Lethal Heat Stress in Natural Settings. Adult Flies Eclosing from Wild Larvae that Had Survived Natural Heat Stress Exhibited Severe Developmental Anomalies of Wing and Abdominal Morphology, Which Should Dramatically Affect Fitness. the Frequency of Developmental Abnormalities Varied Along Two Independent …