Open Access. Powered by Scholars. Published by Universities.®
Ecology and Evolutionary Biology Commons™
Open Access. Powered by Scholars. Published by Universities.®
Articles 1 - 1 of 1
Full-Text Articles in Ecology and Evolutionary Biology
Evolution Of Voltage-Gated Ion Channels, Kevin Gregory Bennett, Kevin Bennett
Evolution Of Voltage-Gated Ion Channels, Kevin Gregory Bennett, Kevin Bennett
Master of Science in Integrative Biology Theses
Voltage-gated Ion Channels (VICs) form a superfamily of energy-independent membrane transporters that facilitate the transfer of charged sodium, calcium, and potassium ions across the cell membrane (Hodgkin & Huxley 1952). The channels contain a selective ion-conducting pore along with several other structural and gating features that come together to form a functional hetero- or homotetramer. A comprehensive phylogenetic study of all available proteins aimed at finding unknown distribution and illuminating evolutionary paths would be immensely useful in understanding relationships of structure, function, and organismal distribution. This phylogenetic analysis of VICs will be immensely useful in characterizing functional and structural distribution, …