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Full-Text Articles in Cell and Developmental Biology
The Role Of T-Box Proteins In Vertebrate Germ Layer Formation And Patterning, Sushma Teegala
The Role Of T-Box Proteins In Vertebrate Germ Layer Formation And Patterning, Sushma Teegala
Dissertations, Theses, and Capstone Projects
All of the tissues in triploblastic organisms, with the exception of the germ cells, arise from the three germ layers, ectoderm, mesoderm and the endoderm. The identification of the genes that underlie the differentiation of these layers is crucial to our understanding of development. T-box family proteins are DNA-binding transcriptional regulators that play important roles during germ layer formation in the early vertebrate embryo. Well-characterized members of this family, including the transcriptional activators Brachyury and VegT, are essential for the proper formation of mesoderm and endoderm, respectively. To date, T-box proteins have not been shown to play a role in …
Methylglyoxal Influences Development Of Caenorhabditis Elegans Via Heterochronic Pathway, Jiaying Wang
Methylglyoxal Influences Development Of Caenorhabditis Elegans Via Heterochronic Pathway, Jiaying Wang
Masters Theses
Methylglyoxal is a highly reactive dicarbonyl compound, which is widely distributed in food products and beverages, and is particularly high in Manuka honey. In addition to its antibacterial effects, methylglyoxal is also known as a major precursor of advanced glycation end products (AGEs), that produces altered macromolecules (such as proteins and DNA), leading to abnormal physiological changes. However, the effects of methylglyoxal on development is unclear. Thus, this study aimed to determine the role of methylglyoxal in this aspect using Caenorhabditis elegans (C. elegans). Treatment of methylglyoxal at 0.1 mM and 1 mM for 48 h significantly inhibited …
The Role Of Phototaxis In The Initial Swim Bladder Inflation Of Larval Yellow Perch (Perca Flavescens)., Christopher Ryan Suchocki
The Role Of Phototaxis In The Initial Swim Bladder Inflation Of Larval Yellow Perch (Perca Flavescens)., Christopher Ryan Suchocki
Theses and Dissertations
The North Central Regional Aquaculture Center has designated the yellow perch (Perca flavescens) as a high priority species for culture. The demand for this species is high and it is estimated that the market could readily consume 50 to 100 million pounds per year. Tank culturing of yellow perch has several advantages over pond culture and this method has been growing in popularity, but is currently held back by problems in larval development. One of these problems, failed swim bladder inflation (SBI), is frequently reported in the literature as a bottleneck in the culture of many fishes. Unsuccessful SBI increases …
Development Of Mechanosensory Innervation In The Frog, Xenopus Laevis, Peter Andrew Feuk
Development Of Mechanosensory Innervation In The Frog, Xenopus Laevis, Peter Andrew Feuk
Theses and Dissertations
ABSTRACT
DEVELOPMENT OF MECHANOSENSORY INNERVATION IN THE FROG, XENOPUS LAEVIS
by
Peter Feuk
The University of Wisconsin-Milwaukee, 2017
Under the Supervision of Dr. R. David Heathcote
This study aims to investigate whether a specific target cell in the epidermis of the African clawed frog, Xenopus laevis, guides the initial outgrowth and pattern of Rohon-Beard (RB) cells and their survival. RB cells are primary mechanosensory neurons present during the early developmental stages of X. laevis. These neurons provide sensory input to the frog throughout embryonic and larval development before initiating apoptosis around the start of metamorphosis. The innervation of embryonic skin …
Zebrafish (Danio Rerio) As A Model For Orofacial Research, Kevin A. Ghaffari
Zebrafish (Danio Rerio) As A Model For Orofacial Research, Kevin A. Ghaffari
Theses and Dissertations
Across species, the face and more specifically the mouth, serves as an essential facet of everyday life. Amongst humans the mouth serves as a tool for the ingestion of food, a marker for facial recognition and a medium for communication. In order for the mouth to properly form, a series of precise growth and fusion events are needed. In order to insure that these events are orchestrated properly is a wide array of signals, transcription factors and epigenetic regulators. Due to the needed precision of these events, congenital birth defects of the face such as cleft lip and cleft palate …
Vein Patterning During Juvenile Wing Development In Oncopeltus Fasciatus And Jadera Haematoloma, William R. Simmons
Vein Patterning During Juvenile Wing Development In Oncopeltus Fasciatus And Jadera Haematoloma, William R. Simmons
Honors Theses
Wings are a defining characteristic of all pterygote insects and are agreed to originate from a single common winged ancestor. However, essentially nothing is known about the molecular mechanisms that regulate wing development and patterning outside of Endopterygota, and the vast majority of this knowledge comes solely from Drosophila melanogaster. There is reason to suspect that the drastic developmental differences that exist between Endopterygota and Exopterygota have resulted in changes in the mechanisms, timings, or even genes that govern wing development. This study examined the roles of several genes known to be involved in D. melanogaster wing development and patterning …