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Full-Text Articles in Biology

Two Drosophila Suppressors Of Cytokine Signaling (Socs) Differentially Regulate Jak And Egfr Pathway Activities, Jason S. Rawlings, Gabriela Rennebeck, Susan M.W. Harrison, Rongwen Xi, Douglas A. Harrison Oct 2004

Two Drosophila Suppressors Of Cytokine Signaling (Socs) Differentially Regulate Jak And Egfr Pathway Activities, Jason S. Rawlings, Gabriela Rennebeck, Susan M.W. Harrison, Rongwen Xi, Douglas A. Harrison

Biology Faculty Publications

BACKGROUND: The Janus kinase (JAK) cascade is an essential and well-conserved pathway required to transduce signals for a variety of ligands in both vertebrates and invertebrates. While activation of the pathway is essential to many processes, mutations from mammals and Drosophila demonstrate that regulation is also critical. The SOCS (Suppressor Of Cytokine Signaling) proteins in mammals are regulators of the JAK pathway that participate in a negative feedback loop, as they are transcriptionally activated by JAK signaling. Examination of one Drosophila SOCS homologue, Socs36E, demonstrated that its expression is responsive to JAK pathway activity and it is capable of downregulating …


Genetic Diversity Of Peanut (Arachis Hypogaea L.) And Its Wild Relatives Based On The Analysis Of Hypervariable Regions Of The Genome, Marcio De Carvalho Moretzsohn, Mark S. Hopkins, Sharon E. Mitchell, Stephen Kresovich, Jose Francisco Montenegro Valls, Marcio Elias Ferreira Jul 2004

Genetic Diversity Of Peanut (Arachis Hypogaea L.) And Its Wild Relatives Based On The Analysis Of Hypervariable Regions Of The Genome, Marcio De Carvalho Moretzsohn, Mark S. Hopkins, Sharon E. Mitchell, Stephen Kresovich, Jose Francisco Montenegro Valls, Marcio Elias Ferreira

Faculty Publications

Background: The genus Arachis is native to a region that includes Central Brazil and neighboring countries. Little is known about the genetic variability of the Brazilian cultivated peanut (Arachis hypogaea, genome AABB) germplasm collection at the DNA level. The understanding of the genetic diversity of cultivated and wild species of peanut (Arachis spp.) is essential to develop strategies of collection, conservation and use of the germplasm in variety development. The identity of the ancestor progenitor species of cultivated peanut has also been of great interest. Several species have been suggested as putative AA and BB genome donors …


Construction Of The Bac Library For Biomphalaria Glabrata, Coen Adema Jan 2004

Construction Of The Bac Library For Biomphalaria Glabrata, Coen Adema

Biomphalaria Genome Initiative

No abstract provided.


Full-Length Mitochondrial Genome Sequence Of Biomphalaria Glabrata, Coen Adema Jan 2004

Full-Length Mitochondrial Genome Sequence Of Biomphalaria Glabrata, Coen Adema

Biomphalaria Genome Initiative

No abstract provided.