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Full-Text Articles in Biology
Sex Differences In The Co-Expression Of Estrogen Receptor Alpha With Corticotropin Releasing Factor, Deborah Ariyibi
Sex Differences In The Co-Expression Of Estrogen Receptor Alpha With Corticotropin Releasing Factor, Deborah Ariyibi
Biological Sciences
Women are far more likely to develop anxiety and depression than men. It is believed that the dysregulation of the HPA axis by the binding of corticotropin -releasing factor (CRF) to the corticotropin-releasing factor receptor 1 (CRFR1) contributes to the likelihood of these stress- related disorders. Estrogens acting through Estrogen receptor alpha (ERa) have been shown to increase anxiety production upon activating the HPA axis. In this current study, we explored whether CRF-expressing neurons in various regions of the brain express ERa. The levels of ERa were counted in the bed nucleus of the stria terminalis (BST), the medial preoptic …
Estrogen Modulation Of Vta Dopamine Neuron Physiology And Behavioral Responsivity To Variable Social Stressors, Mary R. Shanley
Estrogen Modulation Of Vta Dopamine Neuron Physiology And Behavioral Responsivity To Variable Social Stressors, Mary R. Shanley
Dissertations, Theses, and Capstone Projects
The behavioral output of different animals, or even the same animal in different contexts, is remarkably variable in response to the same external stimulus. This behavioral diversity is due to the complex integration of external and internal stimuli, through both neuronal and hormonal signals that selects the best behavioral response. By their nature as long-distance signaling molecules, hormones play a critical role in communicating information about internal states across the organism. Many hormones produced in the periphery target the central nervous system to modulate animal behavior, selecting for behaviors that are appropriate over behaviors that are maladaptive in that specific …
Effects Of Synthetic Estrogen (17Α-Ethinyl Estradiol) On Male Fiddler Crab Aggression, Micayla Shirley
Effects Of Synthetic Estrogen (17Α-Ethinyl Estradiol) On Male Fiddler Crab Aggression, Micayla Shirley
Honors College Theses
Pharmaceuticals, including hormones and antibiotics, are considered contaminants due to their widespread use and release into the environment. Hormones, like the synthetic estrogen used in oral contraceptives (17α-ethinylestradiol), are present in freshwater and marine systems, but with relatively unknown effects on the organisms that live there. Ethinylestradiol (EE2) accumulates in waterlogged soil (sediment) with potential to harm sediment-dwelling animals. For example, fiddler crabs (Uca pugilator) are vital members of salt marsh communities. Their burrowing adds oxygen to sediments and cycles nutrients, and they are an important food resource to birds and raccoons. Male fiddler crabs are territorial, aggressively …
Estrogen Disruption Of Hypothalamic Neural Activity, Princess Dickson
Estrogen Disruption Of Hypothalamic Neural Activity, Princess Dickson
Cal Poly Humboldt theses and projects
The brain is highly dependent on the endocrine system for proper neurodevelopment, as it plays a key role in many biological processes. Bisphenol A is a chemical found in plastics that has the potential to mimic the effects of Estrogen in the body, at least weakly. People interact with plastic that contains BPA regularly, and people are at risk for exposure even before being born. The abundance of BPA, along with other exogenous estrogens, makes examining the relationship between early exposure and changes in brain activity imperative. The current study aims to establish a relationship between disrupted estrogen function and …