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Full-Text Articles in Biology

Regeneration Of Retinotectal Projections After Optic Tectum Removal In Adult Newts, Mitsumasa Okamoto, Hatsuki Ohsawa, Toshinori Hayashi, Katsushi Owaribe, Panagiotis A. Tsonis Nov 2007

Regeneration Of Retinotectal Projections After Optic Tectum Removal In Adult Newts, Mitsumasa Okamoto, Hatsuki Ohsawa, Toshinori Hayashi, Katsushi Owaribe, Panagiotis A. Tsonis

Biology Faculty Publications

Purpose: When injured, the adult newt possesses the remarkable capability to regenerate tissues and organs with return of function and physiology. One example is the newt eye, in which regeneration can restore normal vision if the retina or lens has been removed. We wanted to examine how the retinotectal projections regenerate after removal of the brain’s optic tectum and establish this animal as a model for retinal projection as well as a central nervous system regeneration model.


Neural Defects And Cardiac Arrhythmia In Fish Larvae Following Embryonic Exposure To 2,2',4,4'-Tetrabromodiphenyl Ether (Pbde 47), Sean C. Lema, Irvin R. Schultz, Nathaniel L. Scholz, John P. Incardona, Penny Swanson May 2007

Neural Defects And Cardiac Arrhythmia In Fish Larvae Following Embryonic Exposure To 2,2',4,4'-Tetrabromodiphenyl Ether (Pbde 47), Sean C. Lema, Irvin R. Schultz, Nathaniel L. Scholz, John P. Incardona, Penny Swanson

Biological Sciences

Polybrominated diphenyl ethers (PBDEs) are added to plastics, polyurethane foam, and textiles as a flame retardant. While PBDEs play a key role in reducing loss of human life and property from fires, these flame retardants have become pervasive organic contaminants in the environment and in the tissues of fish, birds, marine mammals, and humans. Levels of PBDEs in wildlife and humans continue to rise, raising concerns about potential ecological and health risks associated with exposure to these chemicals. Nevertheless, there is little currently known about the toxicological effects of PBDE exposure. Here, we examined the developmental toxicity of the PBDE …