Biology Commons^™

Assessing Biomass Fuel Consumption In Kasigau, Kenya As A Predictor Of Hypertension, Conner Hounshell

Mahurin Honors College Capstone Experience/Thesis Projects

Cardiovascular disease is the leading cause of death globally and disproportionately affects low- and middle-income countries, such as Kenya. Hypertension is the leading risk factor for cardiovascular disease and is influenced by a variety of factors such as diet, tobacco use, and genetics. One such factor linked to hypertension is exposure to air pollution, but minimal research exists on the effects of household air pollution. Hypertension that is not related to common Western risk indicators, such as waist-to-hip ratio, body mass indices, and hypercholestorlemia, is prevalent in the community of Kasigau, Kenya, along with the prevalence of risks for household …

Correlation Of Environmental Risks With The Prevalence Of Essential Hypertension And Chronic Cardiac Disease In Kasigau, Kenya, Addie Dodson

Mahurin Honors College Capstone Experience/Thesis Projects

Cardiovascular disease (CVD) is a chronic non-communicable disease (NCD) that is the leading cause of death across the world. In developing nations, like Kenya, the prevalence of NCDs like CVD are on the rise. Hypertension is the major risk factor for CVD and can be influenced by various environmental risk factors, like physical inactivity, unhealthy diets, tobacco use, and alcohol use. Though these are known factors that can affect blood pressure in developed nations, research over the prevalence of essential hypertension (EH) in developing countries is low. In an area in southeast Kenya known as Kasigau, there is a high …

Allelic Variability In The Cyp11b2 C344t Single Nucleotide Polymorphism From A Cohort Of East Africans, Spencer Wright

Mahurin Honors College Capstone Experience/Thesis Projects

Non-communicable disease (NCD), in particular cardiovascular disease, is a significant problem in developing countries. Essential hypertensions (EH) is a leading risk factor for vascular disease and while managing EH in developing countries is considered a high global priority, few studies exist from third world populations. From a cohort of Kenyans living in the Kasigau region, we have investigated the allele frequency of a single nucleotide polymorphism (SNP) previously reported to correlate with salt-sensitive EH. The SNP being investigated is aldosterone synthase CYP11B2 C344T (rs1799998), a polymorphism in the renin-angiotensin system (RAS). The C344T polymorphism is located in the promoter region …

The Prevalence Of Essential Hypertension In Kasigau, Kenya, Lindsay Williams

Mahurin Honors College Capstone Experience/Thesis Projects

Hypertension is the leading cause of cardiovascular disease worldwide. Cardiovascular disease (CVD) is a widespread chronic non-communicable disease (NCD) which is on the rise in developing countries. Evidence based on extensive research studies on risk factors for NCDs suggests that they could be easily significantly decreased by simply controlling their risk factors. Although high blood pressure has been recognized as a leading risk factor for CVD, little research has been done to document the prevalence and incidence of essential hypertension (EH) in lower socioeconomic developing countries. One such country is Kenya. It was found in our research study that Kasigau …

Assessing Social Benefits Of Domestic Rainwater Harvesting In Southern Kenya, Lindsey M. Filiatreau

Mahurin Honors College Capstone Experience/Thesis Projects

In the Kasigau location of the Voi District of Kenya, severe rainwater shortages closed fourteen water collection stations in 2008 and 2009, leaving ten water sources to service 15,000 people in the region. Few families in the area have domestic rainwater harvesting systems which are an easily implemented, low-cost means of water collection. I investigated the ability of rainwater catchment systems to modify family time budgets (by reducing water collection time) and lessen the severity of water scarcity (by supplying families a significant amount of water). Forty families participated in the research, 20 of whom received free installation of a …

Assessment Of Prenatal Care And Perinatal Outcomes In Kasigau, Kenya, Allison Smith

Mahurin Honors College Capstone Experience/Thesis Projects

The World Health Organization (WHO) implemented the Millennium Declaration in 2000 to establish global health goals to be achieved by 2015. Two of these Millennium Development Goals (MDG’s) are directly related to maternal, neonatal and child health. Healthcare during the prenatal period can help achieve the WHO MDG’s for maternal health and child mortality. Evidence has shown that women in Kenya have limited access to prenatal care. This study focused on the prenatal care and postnatal outcome trends of the women in Kasigau, Kenya. Participants were surveyed in three villages (Rukanga, Makwasinyi, and Bhuguta) to determine if prenatal care was …

Human-Wildlife Conflict On Small, Subsistence Farms In Kenya, Christopher B. Colonna

Mahurin Honors College Capstone Experience/Thesis Projects

As human populations expand, wildlife suddenly competes with humans for resources and confrontation arises as a result. Rural Africa is typical of this problem. We surveyed local owners of small farms within the five villages surrounding Mount Kasigau in Southeast Kenya to quantify losses due to wildlife depredation on both subsistence and cash crops as well as to discover the patterns and variables influencing farmer-wildlife confrontations in the region. We found no statistically significant correlations among the value of damage per acre, the distance from the bush, or the distance to the nearest water source. We did find statistical significance …

A New Genus Of Soft Coral Of The Family Alcyoniidae (Cnidaria, Octocorallia) With Re-Description Of A New Combination And Description Of A New Species, Catherine S. Mcfadden, Yehuda Benayahu

All HMC Faculty Publications and Research

A new genus, Aldersladum (family Alcyoniidae), is established to accommodate a previously described species, Effl atounaria sodwanae Benayahu, 1993 (family Xeniidae) from Sodwana Bay, South Africa that was wrongly assigned to the latter genus. Th is species is redescribed and a second new species, A. jengi from Penghu Is., Taiwan, is described. Th e diagnostic features of the new genus include the presence of only figure-eight shaped platelets in all parts of the colony, thus differentiating it from all known genera of the Alcyoniidae. Based on examination of additional material from other localities, the zoogeographical distribution of the genus is …

A Note On The Thermal Ecology And Foraging Behaviour Of The Egyptian Fruit Bat, Rousettus Aegyptiacus, At Mt. Elgon, Kenya, Donald A. Mcfarlane, Joyce Lundberg

WM Keck Science Faculty Papers

The Egyptian fruit bat, Rousettus aegyptiacus, is an abundant and widely distributed African pteropid (Nowak, 1999). The species is unusual amongst pteropids in being an obligate cave-dweller (Kwiecinski & Griffiths, 1999), sometimes reaching colony sizes in the thousands (Kingdon, 1974). In the caves of Mt. Elgon National Park, western Kenya (1° 08′N, 34° 39′E), precision temperature loggers placed in major Rousettus roosts and intervening passages have allowed us to precisely monitor bat emergence and return times.

The major caves of Mt. Elgon National Park consist of geophagically modified tunnels and collapse chambers cut into Miocene-aged pyroclastic strata (Lundberg & …

D1s80 Single-Locus Discrimination Among African Populations, Rene J. Herrera, Leslie R. Adrien, Luis M. Ruiz, Nahir Y. Sanabria, George Duncan

Biology Faculty Articles

The highly polymorphic D1S80 locus has no known genetic function. However, this variable number of tandem repeats (VNTR) locus has been highly valuable in forensic identification. In this study we report the allele and genotype frequencies of five African populations (Benin, Cameroon, Egypt, Kenya, and Rwanda), which can be used as databases to help characterize populations and identify individuals. The allele frequencies were used to infer genetic associations through phylogenetic, principal component, and G test statistical analyses. Compliance with Hardy-Weinberg equilibrium expectations was determined as were F_ST estimates, theta p values, and power of discrimination assessment for each population. …