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Full-Text Articles in Biology

Landscape Of Transposable Elements In Mycosphaerella Graminicola, Braham Dhillon, Navdeep Gill, Richard Hamelin, Stephen Goodwin Dec 2014

Landscape Of Transposable Elements In Mycosphaerella Graminicola, Braham Dhillon, Navdeep Gill, Richard Hamelin, Stephen Goodwin

Biology Faculty Articles

Background: In addition to gene identification and annotation, repetitive sequence analysis has become an integral part of genome sequencing projects. Identification of repeats is important not only because it improves gene prediction, but also because of the role that repetitive sequences play in determining the structure and evolution of genes and genomes. Several methods using different repeat-finding strategies are available for whole-genome repeat sequence analysis. Four independent approaches were used to identify and characterize the repetitive fraction of the Mycosphaerella graminicola (synonym Zymoseptoria tritici) genome. This ascomycete fungus is a wheat pathogen and its finished genome comprises 21 chromosomes, eight …


Phenotypic Signatures Arising From Unbalanced Bacterial Growth, Cheemang Tan, Robert P. Smith, Ming-Chi Tsai, Russell Schwartz, Lingchong You Aug 2014

Phenotypic Signatures Arising From Unbalanced Bacterial Growth, Cheemang Tan, Robert P. Smith, Ming-Chi Tsai, Russell Schwartz, Lingchong You

Biology Faculty Articles

Fluctuations in the growth rate of a bacterial culture during unbalanced growth are generally considered undesirable in quantitative studies of bacterial physiology. Under well-controlled experimental conditions, however, these fluctuations are not random but instead reflect the interplay between intra-cellular networks underlying bacterial growth and the growth environment. Therefore, these fluctuations could be considered quantitative phenotypes of the bacteria under a specific growth condition. Here, we present a method to identify “phenotypic signatures” by time-frequency analysis of unbalanced growth curves measured with high temporal resolution. The signatures are then applied to differentiate amongst different bacterial strains or the same strain under …


A Thermal Window For Yawning In Humans: Yawning As A Brain Cooling Mechanism, Jorg J. M. Massen, Kim Dusch, Omar T. Eldakar, Andrew C. Gallup May 2014

A Thermal Window For Yawning In Humans: Yawning As A Brain Cooling Mechanism, Jorg J. M. Massen, Kim Dusch, Omar T. Eldakar, Andrew C. Gallup

Biology Faculty Articles

The thermoregulatory theory of yawning posits that yawns function to cool the brain in part due to counter-current heat exchange with the deep inhalation of ambient air. Consequently, yawning should be constrained to an optimal thermal zone or range of temperature, i.e., a thermal window, in which we should expect a lower frequency at extreme temperatures. Previous research shows that yawn frequency diminishes as ambient temperatures rise and approach body temperature, but a lower bound to the thermal window has not been demonstrated. To test this, a total of 120 pedestrians were sampled for susceptibly to self-reported yawn contagion during …


Progress Of Mesenchymal Stem Cell Therapy For Neural And Retinal Diseases, Tsz Kin Ng, Veronica R. Fortino, Daniel Pelaez, Herman S. Cheung Apr 2014

Progress Of Mesenchymal Stem Cell Therapy For Neural And Retinal Diseases, Tsz Kin Ng, Veronica R. Fortino, Daniel Pelaez, Herman S. Cheung

Biology Faculty Articles

Complex circuitry and limited regenerative power make central nervous system (CNS) disorders the most challenging and difficult for functional repair. With elusive disease mechanisms, traditional surgical and medical interventions merely slow down the progression of the neurodegenerative diseases. However, the number of neurons still diminishes in many patients. Recently, stem cell therapy has been proposed as a viable option. Mesenchymal stem cells (MSCs), a widely-studied human adult stem cell population, have been discovered for more than 20 years. MSCs have been found all over the body and can be conveniently obtained from different accessible tissues: bone marrow, blood, and adipose …


Sequence-Based Analysis Of Structural Organization And Composition Of The Cultivated Sunflower (Helianthus Annuus L.) Genome, Navdeep Gill, Matteo Buti, Nolan Kane, Arnaud Bellec, Nicolas Helmstetter, Hélène Berges, Loren Rieseberg Apr 2014

Sequence-Based Analysis Of Structural Organization And Composition Of The Cultivated Sunflower (Helianthus Annuus L.) Genome, Navdeep Gill, Matteo Buti, Nolan Kane, Arnaud Bellec, Nicolas Helmstetter, Hélène Berges, Loren Rieseberg

Biology Faculty Articles

Sunflower is an important oilseed crop, as well as a model system for evolutionary studies, but its 3.6 gigabase genome has proven difficult to assemble, in part because of the high repeat content of its genome. Here we report on the sequencing, assembly, and analyses of 96 randomly chosen BACs from sunflower to provide additional information on the repeat content of the sunflower genome, assess how repetitive elements in the sunflower genome are organized relative to genes, and compare the genomic distribution of these repeats to that found in other food crops and model species. We also examine the expression …


Programmed Allee Effect In Bacteria Causes A Tradeoff Between Population Spread And Survival, Robert P. Smith, Cheemang Tan, Jaydeep K. Srimani, Anand Pai, Katherine A. Riccione, Hao Song, Lingchong You Mar 2014

Programmed Allee Effect In Bacteria Causes A Tradeoff Between Population Spread And Survival, Robert P. Smith, Cheemang Tan, Jaydeep K. Srimani, Anand Pai, Katherine A. Riccione, Hao Song, Lingchong You

Biology Faculty Articles

Dispersal is necessary for spread into new habitats, but it has also been shown to inhibit spread. Theoretical studies have suggested that the presence of a strong Allee effect may account for these counterintuitive observations. Experimental demonstration of this notion is lacking due to the difficulty in quantitative analysis of such phenomena in a natural setting. We engineered Escherichia coli to exhibit a strong Allee effect and examined how the Allee effect would affect the spread of the engineered bacteria. We showed that the Allee effect led to a biphasic dependence of bacterial spread on the dispersal rate: spread is …


Incorporating A Fitness Goal Into The Fabric Of Your Life, Emily F. Schmitt Lavin Jan 2014

Incorporating A Fitness Goal Into The Fabric Of Your Life, Emily F. Schmitt Lavin

Biology Faculty Articles

No abstract provided.


Winner And Loser Effects In Major League Baseball Double Headers, Andrew C. Gallup, Omar T. Eldakar Jan 2014

Winner And Loser Effects In Major League Baseball Double Headers, Andrew C. Gallup, Omar T. Eldakar

Biology Faculty Articles

Across the animal kingdom it has been observed that outcomes of conflicts are influenced by past experiences, whereby previous winners are likely to keep winning and losers are likely to lose again. These so-called “winner and loser effects” are hypothesized to result from factors such as information acquisition and endocrine responses following the initial bouts. This paper applies the understanding of this phenomenon to a novel domain: patterns of winning and losing in Major League Baseball (MLB) double headers. By accessing archival data available from www.espn.com, we report on the incidence of a single team winning both games (sweeps) versus …


Correction: Evidence For The Requirement Of 14-3-3eta (Ywhah) In Meiotic Spindle Assembly During Mouse Oocyte Maturation, Santanu De, Douglas Kline Jan 2014

Correction: Evidence For The Requirement Of 14-3-3eta (Ywhah) In Meiotic Spindle Assembly During Mouse Oocyte Maturation, Santanu De, Douglas Kline

Biology Faculty Articles

No abstract provided.