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Full-Text Articles in Biology
Aberrant Methylation Of Polo-Like Kinase Cpg Islands In Plk4 Heterozygous Mice, Alejandra Ward, Alan Morettin, Shum, David Shum, David, John W. Hudson
Aberrant Methylation Of Polo-Like Kinase Cpg Islands In Plk4 Heterozygous Mice, Alejandra Ward, Alan Morettin, Shum, David Shum, David, John W. Hudson
Biological Sciences Publications
Hepatocellular carcinoma (HCC), one of the most common cancers world-wide occurs twice as often in men compared to women. Predisposing conditions such as alcoholism, chronic viral hepatitis, aflatoxin B1 ingestion, and cirrhosis all contribute to the development of HCC.
Anthropogenic Noise Affects Song Structure In Red-Winged Blackbirds (Agelaius Phoeniceus), Dalal Hanna, Gabriel Blouin-Demers, David R. Wilson, Daniel J. Mennill
Anthropogenic Noise Affects Song Structure In Red-Winged Blackbirds (Agelaius Phoeniceus), Dalal Hanna, Gabriel Blouin-Demers, David R. Wilson, Daniel J. Mennill
Biological Sciences Publications
Anthropogenic noise can mask animal signals that are crucial for communicating information about food, predators and mating opportunities. In response to noise masking, signallers can potentially improve acoustic signal transmission by adjusting the timing, frequency or amplitude of their signals. These changes can be a short-term modification in response to transient noise or a long-term modification in response to chronic noise. An animal's ability to adapt to anthropogenic noise can be crucial to its success. In this study, we evaluated the effects of anthropogenic noise on the structure of red-winged blackbird song. First, we manipulated the presence of anthropogenic noise …
Communal Or Competitive? Stable Isotope Analysis Provides Evidence Of Resource Partitioning Within A Communal Shark Nursery, M. J. Kinney, N. E. Hussey, A. T. Fisk, A. J. Tobin, C. A. Simpfendorfer
Communal Or Competitive? Stable Isotope Analysis Provides Evidence Of Resource Partitioning Within A Communal Shark Nursery, M. J. Kinney, N. E. Hussey, A. T. Fisk, A. J. Tobin, C. A. Simpfendorfer
Biological Sciences Publications
No abstract provided.
Human Activity Helps Prey Win The Predator-Prey Space Race, Tyler B. Muhly, Christina A. D. Semeniuk, Alessandro Massolo, Laura Hickman, Marco Musiani
Human Activity Helps Prey Win The Predator-Prey Space Race, Tyler B. Muhly, Christina A. D. Semeniuk, Alessandro Massolo, Laura Hickman, Marco Musiani
Biological Sciences Publications
Predator-prey interactions, including between large mammalian wildlife species, can be represented as a “space race”, where prey try to minimize and predators maximize spatial overlap. Human activity can also influence the distribution of wildlife species. In particular, high-human disturbance can displace large carnivore predators, a trait-mediated direct effect. Predator displacement by humans could then indirectly benefit prey species by reducing predation risk, a trait-mediated indirect effect of humans that spatially decouples predators from prey. The purpose of this research was to test the hypothesis that high-human activity was displacing predators and thus indirectly creating spatial refuge for prey species, helping …
Further Analysis Supports The Conclusion That The Songs Of Screaming Pihas Are Individually Distinctive And Bear A Lek Signature, Lauren P. Fitzsimmons, Nicole K. Barker, Daniel J. Mennill
Further Analysis Supports The Conclusion That The Songs Of Screaming Pihas Are Individually Distinctive And Bear A Lek Signature, Lauren P. Fitzsimmons, Nicole K. Barker, Daniel J. Mennill
Biological Sciences Publications
No abstract provided.
Oceanic Sharks Clean At Coastal Seamount, S. P. Oliver, N. E. Hussey, Turner, J.R. Turner, J.R., A. J. Beckett
Oceanic Sharks Clean At Coastal Seamount, S. P. Oliver, N. E. Hussey, Turner, J.R. Turner, J.R., A. J. Beckett
Biological Sciences Publications
No abstract provided.
Water Hyacinth (Eichhornia Crassipes) And Water Lettuce (Pistia Stratiotes) In The Great Lakes: Playing With Fire?, A. A. Adebayo, Briski, E. Briski, E., O. Kalaci, M. Hernandez, S. Ghabooli, B. Beric, F. T. Chan, A. Zhan, E. Fifield, T. Leadley, Hugh J. Macisaac
Water Hyacinth (Eichhornia Crassipes) And Water Lettuce (Pistia Stratiotes) In The Great Lakes: Playing With Fire?, A. A. Adebayo, Briski, E. Briski, E., O. Kalaci, M. Hernandez, S. Ghabooli, B. Beric, F. T. Chan, A. Zhan, E. Fifield, T. Leadley, Hugh J. Macisaac
Biological Sciences Publications
The Laurentian Great Lakes have been successfully invaded by at least 182 nonindigenous species. Here we report on two new species, water hyacinth Eichhornia crassipes and water lettuce Pistia stratiotes, that were found at a number of locations in Lake St. Clair and Detroit River during autumn 2010. Both species are commonly sold in the water garden and aquarium trade in southern Ontario and elsewhere. While it is not clear whether these species are established or can establish in the Great Lakes, the historic assumption that neither of these subtropical to tropical plants pose an invasion risk must be questioned …
Cathepsin B: A Potential Prognostic Marker For Inflammatory Breast Cancer., Nouh A. Mohamed, Mona M. Mohamed, Mohamed El-Shinawi, Mohamed A. Shaalan, Dora Cavallo-Medved, Hussein M. Khaled, Bonnie F. Sloane
Cathepsin B: A Potential Prognostic Marker For Inflammatory Breast Cancer., Nouh A. Mohamed, Mona M. Mohamed, Mohamed El-Shinawi, Mohamed A. Shaalan, Dora Cavallo-Medved, Hussein M. Khaled, Bonnie F. Sloane
Biological Sciences Publications
Inflammatory breast cancer (IBC) is the most aggressive form of breast cancer. In non-IBC, the cysteine protease cathepsin B (CTSB) is known to be involved in cancer progression and invasion; however, very little is known about its role in IBC. In this study, we enrolled 23 IBC and 27 non-IBC patients. All patient tissues used for analysis were from untreated patients. Using immunohistochemistry and immunoblotting, we assessed the levels of expression of CTSB in IBC versus non-IBC patient tissues. Previously, we found that CTSB is localized to caveolar membrane microdomains in cancer cell lines including IBC, and therefore, we also …
Inhibition Of Cathepsin B Activity Attenuates Extracellular Matrix Degradation And Inflammatory Breast Cancer Invasion., Bernadette C. Victor, Arulselvi Anbalagan, Mona M. Mohamed, Dora Cavallo-Medved, Bonnie F. Sloane
Inhibition Of Cathepsin B Activity Attenuates Extracellular Matrix Degradation And Inflammatory Breast Cancer Invasion., Bernadette C. Victor, Arulselvi Anbalagan, Mona M. Mohamed, Dora Cavallo-Medved, Bonnie F. Sloane
Biological Sciences Publications
Inflammatory breast cancer (IBC) is an aggressive, metastatic and highly angiogenic form of locally advanced breast cancer with a relatively poor three-year survival rate. Breast cancer invasion has been linked to proteolytic activity at the tumor cell surface. Here we explored a role for active cathepsin B on the cell surface in the invasiveness of IBC. We examined expression of the cysteine protease cathepsin B and the serine protease urokinase plasminogen activator (uPA), its receptor uPAR and caveolin-1 in two IBC cell lines: SUM149 and SUM190. We utilized a live cell proteolysis assay to localize in real time the degradation …