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Full-Text Articles in Biology

Competitive Replacement Of Invasive Congeners May Relax Impact On Native Species: Interactions Among Zebra, Quagga, And Native Unionid Mussels, Lyubov E. Burlakova, Brianne L. Tulumello, Alexander Y. Karatayev, Robert A. Krebs, Donald W. Schloesser, Wendy L. Paterson, Traci A. Griffith, Mariah W. Scott, Todd Crail, David T. Zanatta Dec 2014

Competitive Replacement Of Invasive Congeners May Relax Impact On Native Species: Interactions Among Zebra, Quagga, And Native Unionid Mussels, Lyubov E. Burlakova, Brianne L. Tulumello, Alexander Y. Karatayev, Robert A. Krebs, Donald W. Schloesser, Wendy L. Paterson, Traci A. Griffith, Mariah W. Scott, Todd Crail, David T. Zanatta

Biological, Geological, and Environmental Faculty Publications

Determining when and where the ecological impacts of invasive species will be most detrimental and whether the effects of multiple invaders will be superadditive, or subadditive, is critical for developing global management priorities to protect native species in advance of future invasions. Over the past century, the decline of freshwater bivalves of the family Unionidae has been greatly accelerated by the invasion of Dreissena. The purpose of this study was to evaluate the current infestation rates of unionids by zebra (Dreissena polymorpha) and quagga (D. rostriformis bugensis) mussels in the lower Great Lakes region 25 …


Ecosystem Regime Change Inferred From The Distribution Of Trace Metals In Lake Erie Sediments, Fasong Yuan, Richard Depew, Cheryl Soltis-Muth Dec 2014

Ecosystem Regime Change Inferred From The Distribution Of Trace Metals In Lake Erie Sediments, Fasong Yuan, Richard Depew, Cheryl Soltis-Muth

Biological, Geological, and Environmental Faculty Publications

Many freshwater and coastal marine ecosystems across the world may have undergone an ecosystem regime change due to a combination of rising anthropogenic disturbances and regional climate change. Such a change in aquatic ecosystems is commonly seen as shifts in algal species. But considerably less detail is known about the eutrophication history in terms of changes in algal productivity, particularly for a large lake with a great deal of spatial variability. Here we present an analysis of trace metals (Cu, Ni, Cd, and Pb) on a sediment core recovered from Lake Erie, off the Vermilion coast of northern Ohio, USA, …


Suppression Of Subtelomeric Vsg Switching By Trypanosoma Brucei Trf Requires Its Ttaggg Repeat-Binding Activity, Sanaa E. Jehi, Xiaohua Li, Ranjodh Sandhu, Fei Ye, Imaan Benmerzouga, Mingjie Zhang, Yanxiang Zhao, Bibo Li Nov 2014

Suppression Of Subtelomeric Vsg Switching By Trypanosoma Brucei Trf Requires Its Ttaggg Repeat-Binding Activity, Sanaa E. Jehi, Xiaohua Li, Ranjodh Sandhu, Fei Ye, Imaan Benmerzouga, Mingjie Zhang, Yanxiang Zhao, Bibo Li

Biological, Geological, and Environmental Faculty Publications

Trypanosoma brucei causes human African trypanosomiasis and regularly switches its major surface antigen, VSG, in the bloodstream of its mammalian host to evade the host immune response. VSGs are expressed exclusively from subtelomeric loci, and we have previously shown that telomere proteins TbTIF2 and TbRAP1 play important roles in VSG switching and VSG silencing regulation, respectively. We now discover that the telomere duplex DNA-binding factor, TbTRF, also plays a critical role in VSG switching regulation, as a transient depletion of TbTRF leads to significantly more VSG switching events. We solved the NMR structure of the DNA-binding Myb domain of TbTRF, …


Paired Oxygen Isotope Records Reveal Modern North American Atmospheric Dynamics During The Holocene, Zhongfang Liu, Kei Yoshimura, Gabriel J. Bowen, Nikolaus H. Buenning, Camille Risi, Jeffrey M. Welker, Fasong Yuan Apr 2014

Paired Oxygen Isotope Records Reveal Modern North American Atmospheric Dynamics During The Holocene, Zhongfang Liu, Kei Yoshimura, Gabriel J. Bowen, Nikolaus H. Buenning, Camille Risi, Jeffrey M. Welker, Fasong Yuan

Biological, Geological, and Environmental Faculty Publications

The Pacific North American (PNA) teleconnection has a strong influence on North American climate. Instrumental records and century-scale reconstructions indicate an accelerating tendency towards the positive PNA state since the mid-1850s, but much less is known about long-term PNA variability. Here we reconstruct PNA-like climate variability during the mid- and late Holocene using paired oxygen isotope records from two regions in North America with robust, anticorrelated isotopic response to the modern PNA. We identify mean states of more negative and positive PNA-like climate during the mid- and late Holocene, respectively. Superimposed on the secular change between states is a robust, …


Atrial Fibrillation Associated Chromosome 4q25 Variants Are Not Associated With Pitx2c Expression In Human Adult Left Atrial Appendages, Shamone R. Gore-Panter, Jeffery Hsu, Peter Hanna, A. Marc Gillinov, Gosta Pettersson, David W. Newton, Christine S. Moravec, David R. Van Wagoner, Mina K. Chung Jan 2014

Atrial Fibrillation Associated Chromosome 4q25 Variants Are Not Associated With Pitx2c Expression In Human Adult Left Atrial Appendages, Shamone R. Gore-Panter, Jeffery Hsu, Peter Hanna, A. Marc Gillinov, Gosta Pettersson, David W. Newton, Christine S. Moravec, David R. Van Wagoner, Mina K. Chung

Biological, Geological, and Environmental Faculty Publications

Atrial Fibrillation (AF), the most common sustained arrhythmia, has a strong genetic component, but the mechanism by which common genetic variants lead to increased AF susceptibility is unknown. Genome-wide association studies (GWAS) have identified that the single nucleotide polymorphisms (SNPs) most strongly associated with AF are located on chromosome 4q25 in an intergenic region distal to the PITX2 gene. Our objective was to determine whether the AF-associated SNPs on chromosome 4q25 were associated with PITX2c expression in adult human left atrial appendages. Analysis of a lone AF GWAS identified four independent AF risk SNPs at chromosome 4q25. Human adult left …


Mitochondrial Dna Variation In The Eastern Pondmussel, Ligumia Nasuta (Bivalvia: Unionoida), In The Great Lakes Region, Mariah Wild Scott, Matthew T. Begley, Robert A. Krebs, David T. Zanatta Jan 2014

Mitochondrial Dna Variation In The Eastern Pondmussel, Ligumia Nasuta (Bivalvia: Unionoida), In The Great Lakes Region, Mariah Wild Scott, Matthew T. Begley, Robert A. Krebs, David T. Zanatta

Biological, Geological, and Environmental Faculty Publications

Most freshwater mussel species in the Great Lakes colonized the region from the Mississippi River basin and few appear to have colonized from Atlantic coast rivers. The Eastern Pondmussel, Ligumia nasuta, is widespread along the Atlantic coast but occurs elsewhere only in the Great Lakes, suggesting that it is one of the few Great Lakes species of Atlantic origin. Great Lakes populations are now imperiled following invasion of the lakes by dreissenid mussels. We examined patterns of diversity in the mitochondrial CO1 and ND1 genes in L. nasuta populations in the Great Lakes and in Atlantic coast rivers. Genetic diversity …