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Dissertations, Master's Theses and Master's Reports

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Cell cycle

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Comparison Of Cell Cycle Gene Expression Between Ovarian Cancer Cell Line Skov3 And Non-Cancerous Cell Lines, Akayla Weatherby Jan 2023

Comparison Of Cell Cycle Gene Expression Between Ovarian Cancer Cell Line Skov3 And Non-Cancerous Cell Lines, Akayla Weatherby

Dissertations, Master's Theses and Master's Reports

Roughly 1% of women will be diagnosed with ovarian cancer during their lifetime. There are many different factors that impact how likely someone is to develop ovarian cancer including age, lifestyle, and family history. Ovarian cancer, like all cancers, occurs due to the accumulation of cancer cells that result from errors in the cell cycle or its regulation. Here, we studied how cell cycle gene expression was altered in the epithelial-like ovarian cancer cell line SKOV3, as compared to the pre-cancerous ovarian cell line FT282, and the non-cancerous foreskin fibroblast cell line BJ5Ta. The three cell lines were synchronized into …