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Exposure Of Phlebotomus Argentipes To Alpha-Cypermethrin, Permethrin, And Ddt Using Cdc Bottle Bioassays To Assess Insecticide Susceptibility, Jacob Rex Andersen
Exposure Of Phlebotomus Argentipes To Alpha-Cypermethrin, Permethrin, And Ddt Using Cdc Bottle Bioassays To Assess Insecticide Susceptibility, Jacob Rex Andersen
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Background: Insecticide resistance for sand flies is a concern since sand flies are vectors for Leishmania spp. parasites which cause leishmaniasis affecting millions of people each year. The CDC bottle bioassay is used to assess resistance by comparing known insecticide diagnostic doses and diagnostic times from an insecticide-susceptible population. The objective of this study was to determine diagnostic doses and diagnostic times for α-cypermethrin and the lethal dose for 50% and 90% mortality for α-cypermethrin, permethrin, and DDT for Phlebotomus argentipes.
Methods: The CDC bottle bioassays were performed in 1,000 mL glass bottles with 15-25 sand flies from a laboratory …