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Molecular And Enzymatic Resistance Of Culex Tarsalis To Pyrethroid And Organophosphate Insecticides, William Mortola
Molecular And Enzymatic Resistance Of Culex Tarsalis To Pyrethroid And Organophosphate Insecticides, William Mortola
University of the Pacific Theses and Dissertations
Culex tarsalis, a vector for diseases like West Nile virus, is evolving resistance to pyrethroid and organophosphate insecticides used for agriculture and vector control in Northern California. Common mechanisms of resistance in other Culex species include the target-site mutations kdr and ace-1 and increased levels of detoxification enzymes (esterases, GSTs, and oxidases). This study contained two parts: Pyrethroid Individual study and an Organophosphate Preliminary study. For the Pyrethroid Individual study, the goal was to compare the prevalence of kdr mutations and detoxification enzymes between pyrethroid susceptible and resistant Cx. tarsalis individuals in Northern California. For the Organophosphate Preliminary study, the …