Open Access. Powered by Scholars. Published by Universities.®

Biology Commons

Open Access. Powered by Scholars. Published by Universities.®

Articles 1 - 3 of 3

Full-Text Articles in Biology

2018 Senior Research Symposium, Otterbein University Department Of Biology & Earth Science Apr 2018

2018 Senior Research Symposium, Otterbein University Department Of Biology & Earth Science

Biology and Earth Science Student Scholarship

This is the schedule for the 2018 Senior Research Symposium and the abstracts from each presentation.


Life Line March 2018, Otterbein Biology And Earth Science Department Mar 2018

Life Line March 2018, Otterbein Biology And Earth Science Department

Life Line - The Biology Department Newsletter

Welcome Andrew Calinger-Yoak - Outdoor Laboratory - Conservation Biology - Safari in South Africa - Chengdu Panda Base - Mussells


Characterization Of Two Cyclic Di-Gmp Phosphodiesterases Hypothesized To Regulate Virulence In Streptomyces Scabies, Madison Flasco Jan 2018

Characterization Of Two Cyclic Di-Gmp Phosphodiesterases Hypothesized To Regulate Virulence In Streptomyces Scabies, Madison Flasco

Undergraduate Honors Thesis Projects

Common scab is a devastating disease that affects the marketability of potatoes. The disease results in raised and pitted lesions seen on the surface of the potato and is caused by the soil pathogen, Streptomyces scabies. The S. scabies genome has two cyclic-di-GMP phosphodiesterases, RmdA and RmdB, both regulators of morphology and development. These proteins break down the ubiquitous second messenger molecule cyclic di-GMP, a molecule in charge of cell cycle progression and virulence. Both proteins contain diguanylate cyclase domains and phosphodiesterase domains, GGDEF and EAL, respectively, while RmdA contains an additional PAS_4 domain. Despite similar domain configurations, the two …