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Full-Text Articles in Biology
D1s80 Single-Locus Discrimination Among African Populations, Rene J. Herrera, Leslie R. Adrien, Luis M. Ruiz, Nahir Y. Sanabria, George Duncan
D1s80 Single-Locus Discrimination Among African Populations, Rene J. Herrera, Leslie R. Adrien, Luis M. Ruiz, Nahir Y. Sanabria, George Duncan
Biology Faculty Articles
The highly polymorphic D1S80 locus has no known genetic function. However, this variable number of tandem repeats (VNTR) locus has been highly valuable in forensic identification. In this study we report the allele and genotype frequencies of five African populations (Benin, Cameroon, Egypt, Kenya, and Rwanda), which can be used as databases to help characterize populations and identify individuals. The allele frequencies were used to infer genetic associations through phylogenetic, principal component, and G test statistical analyses. Compliance with Hardy-Weinberg equilibrium expectations was determined as were FST estimates, theta p values, and power of discrimination assessment for each population. …