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Full-Text Articles in Biology
A Computational Investigation Of The Biophysical Mechanisms Underlying Thermotaxis In The Afd Neurons Of Caenorhabditis Elegans, Zachary Mobille
A Computational Investigation Of The Biophysical Mechanisms Underlying Thermotaxis In The Afd Neurons Of Caenorhabditis Elegans, Zachary Mobille
Theses and Dissertations
Thermotaxis in the nematode Caenorhabditis elegans (C. elegans) is studied at the cellular scale of the amphid finger-like ciliated (AFD) neurons, which have previously been shown to be essential for thermoreception. The voltage and calcium signals of AFD during temperature stimuli are described with ordinary differential equations. The primary calcium model is a modified version of that published by Kuramochi and Doi in 2017 to explain the calcium responses of the chemosensitive amphid single-ciliated right (ASER) neuron to fluctuations in extracellular salt concentration. To account for the effects of temperature, changes to the stimuli conditions under which inactivation takes place …
The Reemergence Of Eradicated Disease Due To Ecological Impact Of Climate Change, Claudia Kolakowski
The Reemergence Of Eradicated Disease Due To Ecological Impact Of Climate Change, Claudia Kolakowski
Theses and Dissertations
Global warming is radically changing aspects of the Earth. As scientists continue to research the effects, the ramifications of melting permafrost is coming to light. We build off of a previously existing Anthrax model in the hopes to include climate change as a factor in Anthrax spread. Chapter II develops a simplified version of an Anthrax model. Parameters for the model are found by using previous research and eigenvalues are analyzed in order to find thresholds and equilibria. Chapter III consider the general solutions of the model through eigenvalues and eigenvectors. This model is then extended to include a parameter …
Physiological Consequences Of Neuromodulation And The Cellular Properties That Underlie Them, Margaret Louise Demaegd
Physiological Consequences Of Neuromodulation And The Cellular Properties That Underlie Them, Margaret Louise Demaegd
Theses and Dissertations
Neuronal activity is a product of more than the underlying neuronal connections. Modulatory influences like changes in the animal’s environment, the animals physiological state, or the release of neuromodulators can dramatically alter neuronal activity. Modulatory influences can be beneficial for the animal because they are a source of neuronal and behavioral plasticity, and they can provide neuronal circuits with the robustness needed to continue to function in new conditions, states, or tasks.However, malfunctions of the modulatory system can disrupt neuronal activity and lead to pathologies. Predicting how modulatory influences will alter neuronal activity is challenging because the underlying cellular and …